Journal of Neurogastroenterology and Motility

The Korean Society of Neurogastroenterology and Motility (대한소화기 기능성질환 운동학회)
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Prevalence of Gastric Motility Disorders in Patients with Functional Dyspepsia

  • Asano, Haruki (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Tomita, Toshihiko (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Nakamura, Kumiko (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Yamasaki, Takahisa (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Okugawa, Takuya (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Kondo, Takashi (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Kono, Tomoaki (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Tozawa, Katsuyuki (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Ohda, Yoshio (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Oshima, Tadayuki (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Fukui, Hirokazu (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Fukushima, Kazuhito (Division of Nuclear Medicine and PET Center) ;
  • Hirota, Shozo (Department of Radiology, Hyogo College of Medicine) ;
  • Watari, Jiro (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine) ;
  • Miwa, Hiroto (Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine)
  • Received : 2016.10.13
  • Accepted : 2017.02.08
  • Published : 2017.07.30
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Abstract

Background/Aims Gastric motility abnormalities have been considered to be pathophysiological features of functional dyspepsia (FD) that are closely related to dyspepsia symptoms, especially postprandial distress syndrome (PDS). The aims of this study are to (1) investigate the prevalence of gastric motility disorders and (2) evaluate the association between gastric motility abnormalities and dyspeptic symptoms using gastric scintigraphy in the PDS type of FD. Methods Forty healthy subjects and 94 PDS type FD patients were enrolled in the study. The volunteers and patients ingested a radiolabeled (technetium-99m) solid test meal, and scintigraphic images were recorded. Gastric accommodation and emptying were assessed by scintigraphic imaging. The patients' dyspeptic symptoms were also explored using self-completed symptom questionnaires with 10 variables (4 scales, 0-3 points) at the same time. Results In 94 Japanese FD patients, the prevalence of impaired gastric accommodation and delayed emptying were 14.9% (14/94) and 10.6% (10/94), respectively. Gastric motility abnormalities were seen in 25.5% (24/94) of FD patients. There was no association between gastric motility abnormalities and dyspeptic symptoms. Conclusions Gastric motility abnormalities were seen in 25.5% of Japanese PDS type FD patients. However, there was no association between gastric motility abnormalities and dyspeptic symptoms on gastric scintigraphy.

Keywords

References

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