A Case of Androgenetic Alopecia in an Adolescent Female with Response to Topical Minoxidil

미녹시딜 도포로 호전을 보인 청소년기 여아에서 발생한 안드로겐 탈모증 1예

  • Woo, Young Jun (Department of Dermatology, St. Paul's Hospital, The Catholic University of Korea, College of Medicine) ;
  • Kim, Yoon Seob (Department of Dermatology, St. Paul's Hospital, The Catholic University of Korea, College of Medicine) ;
  • Kim, Jung Eun (Department of Dermatology, St. Paul's Hospital, The Catholic University of Korea, College of Medicine) ;
  • Kang, Hoon (Department of Dermatology, St. Paul's Hospital, The Catholic University of Korea, College of Medicine)
  • 우영준 (가톨릭대학교 의과대학 성바오로병원 피부과학교실) ;
  • 김윤섭 (가톨릭대학교 의과대학 성바오로병원 피부과학교실) ;
  • 김정은 (가톨릭대학교 의과대학 성바오로병원 피부과학교실) ;
  • 강훈 (가톨릭대학교 의과대학 성바오로병원 피부과학교실)
  • Received : 2015.10.01
  • Accepted : 2016.01.06
  • Published : 2017.01.31

Abstract

Androgenetic alopecia (AGA) is a common form of hair loss that usually occurs in the third or fourth decades of life in men, with later onset in women. AGA does rarely occur, however, in the pediatric population. Adolescent AGA is pattern hair loss occurring in boys and girls between 12 and 18 years of age. We herein report the case of a 16-year-old girl with a 5-year history of diffuse hair loss on the crown. Her father had a history of AGA, and the hair pull test was negative. Sex hormone levels and thyroid function test were within the normal range. Phototrichogram analysis revealed diffuse hair thinning over the frontal and vertex areas, and the percentage of vellus hair was higher on the vertex than the occiput. We diagnosed the patient with adolescent AGA. She was prescribed 3% topical minoxidil, and improvement was visible on the clinical photograph and phototrichogram after 2 years of treatment.

Keywords

References

  1. Yoo KH, Rho YK, Kim DH, Park JH, Kim BJ, Kim MN, et al. A Clinical Study of Androgenic Alopecia (VII). Korean J Dermatol 2009;47:765-771
  2. Kim BJ, Kim JY, Eun HC, Kwon OS, Kim MN, Ro BI. Androgenetic alopecia in adolescents: a report of 43 cases. J Dermatol 2006;33:696-699 https://doi.org/10.1111/j.1346-8138.2006.00161.x
  3. Yeo IK, Jang WS, Min PK, Cho HR, Cho SW, Hong NS, et al. An epidemiological study of androgenic alopecia in 3114 Korean patients. Clin Exp Dermatol 2014;39:25-29 https://doi.org/10.1111/ced.12229
  4. Paik JH, Yoon JB, Sim WY, Kim BS, Kim NI. The prevalence and types of androgenetic alopecia in Korean men and women. Br J Dermatol 2001;145:95-99 https://doi.org/10.1046/j.1365-2133.2001.04289.x
  5. Gonzalez ME, Cantatore-Francis J, Orlow SJ. Androgenetic alopecia in the paediatric population: a retrospective review of 57 patients. Br J Dermatol 2010;163:378-385 https://doi.org/10.1111/j.1365-2133.2010.09777.x
  6. Tosti A, Iorizzo M, Piraccini BM. Androgenetic alopecia in children: report of 20 cases. Br J Dermatol 2005;152:556-559 https://doi.org/10.1111/j.1365-2133.2004.06279.x
  7. Jang WS, Son IP, Yeo IK, Park KY, Li K, Kim BJ, et al. The annual changes of clinical manifestation of androgenetic alopecia clinic in korean males and females: a outpatient-based study. Ann Dermatol 2013;25:181-188 https://doi.org/10.5021/ad.2013.25.2.181
  8. Price VH. Androgenetic alopecia in adolescents. Cutis 2003;71:115-121
  9. Mcdonough PH, Schwartz RA. Adolescent androgenic alopecia. Cutis 2011;88:165-168
  10. Blume-Peytavi U, Blumeyer A, Tosti A, Finner A, Marmol V, Trakatelli M, et al. S1 guideline for diagnostic evaluation in androgenetic alopecia in men, women and adolescents. Br J Dermatol 2011;164:5-15 https://doi.org/10.1111/j.1365-2133.2010.10011.x
  11. Kim JE, Lee JH, Choi KH, Lee WS, Choi GS, Kwon OS, et al. Phototrichogram analysis of normal scalp hair characteristics with aging. Eur J Dermatol 2013;23:849-856
  12. Trost LB, Bergfeld WF, Calogeras E. The diagnosis and treatment of iron deficiency and its potential relationship to hair loss. J Am Acad Dermatol 2006;54:824-844 https://doi.org/10.1016/j.jaad.2005.11.1104
  13. Corbo MD, Lam J. Zinc deficiency and its management in the pediatric population: a literature review and proposed etiologic classification. J Am Acad Dermatol 2013;69:616-624 https://doi.org/10.1016/j.jaad.2013.04.028
  14. Alves R, Grimalt R. Hair Loss in Children. Curr Probl Dermatol 2015;47:55-66
  15. Yazdabadi A, Green J, Sinclair R. Successful treatment of female-pattern hair loss with spironolactone in a 9-year-old girl. Australas J Dermatol 2009;50:113-114 https://doi.org/10.1111/j.1440-0960.2009.00517.x