The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Literature Review of Clinical Studies for Herbal Medicine Treatment on Juvenile Idiopathic Arthritis (JIA)

소아 특발성 관절염의 한약치료에 대한 문헌 고찰

  • Kim, Miyeon (Department of Pediatrics, Woosuk University Center) ;
  • Jeong, Minjeong (Department of Pediatrics, College of Korean Medicine, Woosuk University)
  • 김미연 (우석대학교부속한방병원 한방소아과) ;
  • 정민정 (우석대학교 한의과대학 한방소아과학교실)
  • Received : 2018.10.25
  • Accepted : 2018.11.15
  • Published : 2018.11.30
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Abstract

Objectives The purpose of this study is to investigate the clinical studies on the effect of herbal medicine in JIA and to seek better approach of herbal medicine to treat JIA. Methods This study researched randomized controlled trials through various databases in the world about herbal medicine treatments in JIA. Results 11 out of 414 studies were selected and analyzed. All studies were conducted in China. Most of the studies were using herbal medicines, as an adjunctive treatment to the main regimen, and the total effective rate was higher in the treatment group than in the control group. One study was comparing the herbal oriental medicine treatment to the western medicine treatment, and it showed that treatment group was more effective than control group. 5 out of 11 studies reported treatment cases from a single herbal medicine; most of them used Total glucosides of Paeonia (TGP). Clematidis Radix et Rhizoma (威靈仙) were also commonly used, as well as medicinal herbs belong to Eliminating wind-dampness medicine (祛風濕藥) and Activating blood resolving stasis medicine (活血祛瘀藥). Conclusions Based on this study, herbal medicines for JIA treatment will be effective even if used alone or in conjunction with other medicines. To apply clinically, further studies are needed.

Keywords

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Fig. 1. Flow chart of study selection process

Table 3. Constituent of Herbal Medicine of Treatment Group

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Table 4. Frequency of Medical Herbs Composing Herbal Medicine

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Table 5. Classification of Medical Herbs Composing Herbal Medicine

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Table 1. Analysis of Articles (Randomized Controlled Trials; RCTs)

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Table 2. Analysis of Articles (Total Effect Rate)

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