Korean Journal of Organic Agriculture (한국유기농업학회지)

Korean Association of Organic Agriculture (한국유기농업학회)
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Effects of Eco-friendly Multi-enzyme on Diarrhea and Immune Response of weaned Pigs

친환경 복합효소제 첨가가 이유자돈의 설사 및 면역반응에 미치는 영향

  • Min, Ye-Jin (National Institute of Animal Science, Rural Development Administration) ;
  • Kim, Jun-Su (Department of Animal Science and Biotechnology, Chungnam National University) ;
  • Kim, Sheen-A (Department of Animal Science and Biotechnology, Chungnam National University) ;
  • Jang, Ki-Beom (Department of Animal Science and Biotechnology, Chungnam National University) ;
  • Mun, Da-Ye (Department of Animal Science and Biotechnology, Chungnam National University) ;
  • Kim, Byeong-Hyeon (Department of Animal Science and Biotechnology, Chungnam National University) ;
  • Choe, Jee-Hwan (Department of Animal Science and Biotechnology, Chungnam National University) ;
  • Song, Min-Ho (Department of Animal Science and Biotechnology, Chungnam National University)
  • Received : 2018.01.26
  • Accepted : 2018.02.13
  • Published : 2018.02.28
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Abstract

This study was designed to investigate the effects of multi-enzyme on diarrhea and immune responses of weaned pigs. A total 36 weaned pigs ($5.92{\pm}0.48kg\;BW$; 28 d old) were randomly allotted to 2 dietary treatments (3 pigs/pen, 6 replicates/treatment) in a randomized complete block design. The dietary treatments were a typical diet based on corn and soybean meal (CON) and CON with 0.1% multienzyme (Multi; mixture of ${\beta}-mannanase$, xylanase, ${\alpha}-amylase$, protease, ${\beta}-glucanase$, and pectinase). Pigs were fed their respective diets for 6 wk. Frequency of diarrhea, levels of packed cell volume (PCV), white blood cells (WBC), immunoglobulins, cortisol, tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$), transforming growth $factor-{\beta}$ ($TGF-{\beta}$), and C-reactive protein (CRP) were measured. Multi group tended to decrease (p<0.1) diarrhea frequency than CON group during 2 wk after weaning. Lower values of PCV on d 3 (p<0.05) and d 7 (p<0.1) were found in Multi group compared with CON group. There were no significant differences on WBC number and immunoglobulin (Ig) M and A between Multi and CON groups. However, Multi group tended to increase (p<0.1) Ig G on d 7 than CON group. Moreover, Multi group showed modulated immune responses, indicated by decreased levels of cortisol (p<0.05) on d 7 and 14, $TNF-{\alpha}$ on d 3 (p<0.05) and d 7 (p<0.10), $TGF-{\beta}$ on d 2 (p<0.05) and d 7 (p<0.10), and CRP (p<0.10) on d 3 and 7 after weaning compared with CON group. Consequently, inclusion of multi-enzyme in diets for weaned pigs improved gut health and modulated immune responses of weaned pigs.

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References

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