Psychiatry investigation

Korean Neuropsychiatric Association (대한신경정신의학회)
권호 표지
DOI QR코드

DOI QR Code

Psychiatric Findings in Suspected and Confirmed Middle East Respiratory Syndrome Patients Quarantined in Hospital: A Retrospective Chart Analysis

  • Received : 2017.07.04
  • Accepted : 2017.10.25
  • Published : 2018.04.25
⟨ Previous Next ⟩

Abstract

Objective Little is known about the psychiatric complications or risk factors for depression in suspected or confirmed Middle East Respiratory Syndrome (MERS) patients quarantined in hospital. Methods A retrospective chart review was performed of all the patients admitted to the acute MERS inpatient unit at the NMC during the 2015 outbreak. Results 30 (75%) were confirmed to be MERS-CoV positive among 40 admitted cases. Among the 24 MERS survivors, 17 (70.8%) exhibited psychiatric symptoms and 10 (41.7%) received a psychiatric diagnosis and medication during their hospital stay. Suspected MERS patients did not exhibit psychiatric symptoms or receive a psychiatric diagnosis. 27 suspected or confirmed MERS patients (age $41.15{\pm}18.64$, male 37.0%) completed psychological assessments. A multiple linear regression analysis revealed that the Korean National Health and Nutrition Examination Survey-Short form and the Impact of Event Scale-Revised scores were significantly positively correlated with Patient Health Questionnaire-9 scores. Conclusion Our findings indicate that the acute treatment of MERS-CoV infections in quarantine had a significant impact on the patients' mental health. Furthermore, assessment of the risk factors for depression may identify vulnerable patients who require psychiatric care and attention during hospital quarantine.

Keywords

Acknowledgement

Supported by : Korea Health Industry Development Institute (KHIDI)

References

  1. Cho SY, Kang JM, Ha YE, Park GE, Lee JY, Ko JH, et al. MERS-CoV outbreak following a single patient exposure in an emergency room in South Korea: an epidemiological outbreak study. Lancet 2016;388:994-1001. https://doi.org/10.1016/S0140-6736(16)30623-7
  2. Cheng SKW, Tsang JSK, Ku KH, Wong CW, Ng YK. Psychiatric complications in patients with severe acute respiratory syndrome (SARS) during the acute treatment phase: a series of 10 cases. Br J Psychiatry 2004;184:359-360. https://doi.org/10.1192/bjp.184.4.359
  3. Kroenke K, Spitzer RL. The PHQ-9: a new depression diagnostic and severity measure. Psychiatr Ann 2002;32:509-515. https://doi.org/10.3928/0048-5713-20020901-06
  4. Lim HK, Woo JM, Kim TS, Kim TH, Choi KS, Chung SK, et al. Disaster Psychiatry Committee in Korean Academy of Anxiety Disorders. Reliability and validity of the Korean version of the Impact of Event Scale-Revised. Compr Psychiatry 2009;50:385-390. https://doi.org/10.1016/j.comppsych.2008.09.011
  5. Lee ES, Shin HC, Yang YJ, Cho JJ, Ahn KY, Kim SH. Development of the Stress Questionnaire for KNHANES: Report of Scientific Study Service. Seoul: Korea Centers for Disease Control and Prevention; 2010.
  6. Joo H, Ahn H. Development and posttrauma risk checklist. Korean J Psychol Gen 2008;27:235-225.
  7. Wing YK, Leung CM. Mental health impact of severe acute respiratory syndrome: a prospective study. Hong Kong Med J 2012;18(Suppl 3):24-27.
  8. Cheng SK, Wong CW, Tsang J, Wong KC. Psychological distress and negative appraisals in survivors of Severe Acute Respiratory Syndromes (SARS). Psychol Med 2003;34:1187-1195.
  9. Lee AM, Wong JGWS, McAlonan GM, Cheung V, Cheung C, Sham PC, et al. Stress and psychological distress among SARS survivors 1 year after the outbreak. Can J Psychiatry 2007;52:233-240. https://doi.org/10.1177/070674370705200405
  10. Mak IWC, Chu CM, Pan PC, Yiu MGC, Chan VL. Long-term psychiatric morbidities among SARS survivors. Gen Hosp Psychiatry 2009;31: 318-326. https://doi.org/10.1016/j.genhosppsych.2009.03.001
  11. Stanga Z, Field J, Iff S, Stucki A, Lobo DN, Allison SP. The effect of nutritional management on the mood of malnourished patients. Clin Nutr 2007;26:379-382. https://doi.org/10.1016/j.clnu.2007.01.010
  12. Este JA, Cihlar T. Current status and challenges of antiretroviral research and therapy. Antivir Res 2010;85:25-33. https://doi.org/10.1016/j.antiviral.2009.10.007

Cited by

  1. Pandemic and mental adjustment disorders. Therapy options vol.120, pp.5, 2018, https://doi.org/10.17116/jnevro2020120051146
  2. Psycho-Neuroendocrine-Immune Interactions in COVID-19: Potential Impacts on Mental Health vol.11, pp.None, 2018, https://doi.org/10.3389/fimmu.2020.01170
  3. Self-Perceived Stress During the Quarantine of COVID-19 Pandemic in Paraguay: An Exploratory Survey vol.11, pp.None, 2020, https://doi.org/10.3389/fpsyt.2020.558691
  4. A Systematic Review of the Impact of Viral Respiratory Epidemics on Mental Health: An Implication on the Coronavirus Disease 2019 Pandemic vol.11, pp.None, 2018, https://doi.org/10.3389/fpsyt.2020.565098
  5. Adverse Mental Health Impact of the COVID-19 Lockdown in Individuals With Tourette Syndrome in Italy: An Online Survey vol.11, pp.None, 2018, https://doi.org/10.3389/fpsyt.2020.583744
  6. Cognitive and Neuropsychiatric Manifestations of COVID-19 and Effects on Elderly Individuals With Dementia vol.12, pp.None, 2018, https://doi.org/10.3389/fnagi.2020.588872
  7. Mental health consequences of the COVID-19 pandemic associated with social isolation vol.48, pp.4, 2020, https://doi.org/10.5554/22562087.e930
  8. COVID-19 and clinical neuropsychology: A review of neuropsychological literature on acute and chronic pulmonary disease vol.34, pp.7, 2018, https://doi.org/10.1080/13854046.2020.1810325
  9. The Mental Health Consequences of Coronavirus Disease 2019 Pandemic in Dentistry vol.14, pp.6, 2020, https://doi.org/10.1017/dmp.2020.190
  10. Significance and Associated Factors of Long-Term Sequelae in Patients after Acute COVID-19 Infection in Korea vol.53, pp.3, 2018, https://doi.org/10.3947/ic.2021.0022
  11. The SARS-CoV-2 and mental health: From biological mechanisms to social consequences vol.104, pp.None, 2021, https://doi.org/10.1016/j.pnpbp.2020.110046
  12. COVID-19 and post-infectious myalgic encephalomyelitis/chronic fatigue syndrome: a narrative review vol.8, pp.None, 2018, https://doi.org/10.1177/20499361211009385
  13. Qualitative study of the psychological experience of COVID-19 patients during hospitalization vol.278, pp.None, 2018, https://doi.org/10.1016/j.jad.2020.08.040
  14. Sleep and Covid-19 vol.69, pp.1, 2018, https://doi.org/10.4103/0028-3886.310073
  15. Risk of psychological sequelae among coronavirus disease‐2019 survivors: A nationwide cohort study in South Korea vol.38, pp.2, 2021, https://doi.org/10.1002/da.23124
  16. The prevalence of depression, anxiety, and sleep disturbances in COVID‐19 patients: a meta‐analysis vol.1486, pp.1, 2021, https://doi.org/10.1111/nyas.14506
  17. The Impact of the COVID-19 Pandemic on Mental Health: Evidence from Cyprus vol.18, pp.8, 2018, https://doi.org/10.3390/ijerph18083868
  18. Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology vol.26, pp.4, 2018, https://doi.org/10.1038/s41380-020-00965-3
  19. Association between chronic fatigue syndrome and suicidality among survivors of Middle East respiratory syndrome over a 2-year follow-up period vol.137, pp.None, 2018, https://doi.org/10.1016/j.jpsychires.2021.02.029
  20. Rehabilitation strategies and neurological consequences in patients with COVID-19: part I vol.26, pp.3, 2018, https://doi.org/10.1080/10833196.2021.1908729
  21. Anxiety and depressive symptoms among COVID-19 patients admitted to three isolation facilities in Bangladesh vol.8, pp.2, 2018, https://doi.org/10.1177/20551029211046106
  22. Does inflammation link stress to poor COVID‐19 outcome? vol.37, pp.3, 2018, https://doi.org/10.1002/smi.3017
  23. Intensive care unit professionals during the COVID-19 pandemic in Spain: social and work-related variables, COVID-19 symptoms, worries, and generalized anxiety levels vol.36, pp.3, 2018, https://doi.org/10.4266/acc.2021.00213
  24. Association between the severity of new-onset depression and unmet healthcare needs of South Korean adults vol.16, pp.8, 2021, https://doi.org/10.1371/journal.pone.0256222
  25. Modern approaches to the diagnosis and treatment of anxiety disorders associated with a new coronavirus infection vol.10, pp.None, 2021, https://doi.org/10.21518/2079-701x-2021-10-66-79
  26. The Lived Experience of Already-Lonely Older Adults During COVID-19 vol.61, pp.6, 2021, https://doi.org/10.1093/geront/gnab078
  27. Psychological Impact of COVID-19 Pandemic in Bangladesh: Analysis of a Cross-Sectional Survey vol.19, pp.5, 2018, https://doi.org/10.1089/hs.2020.0205
  28. The influence and enlightenment of five public health emergencies on public psychology since new century: A systematic review vol.67, pp.7, 2018, https://doi.org/10.1177/00207640211002222
  29. Prevalence and predictors of posttraumatic stress disorder, depression and anxiety among hospitalized patients with coronavirus disease 2019 in China vol.21, pp.1, 2018, https://doi.org/10.1186/s12888-021-03076-7
  30. COVID-19: the perfect vector for a mental health epidemic vol.45, pp.6, 2018, https://doi.org/10.1192/bjb.2020.60
  31. Prevalence and factors associated with anxiety and depression amongst hospitalised COVID-19 patients in Laquintinie Hospital Douala, Cameroon vol.16, pp.12, 2021, https://doi.org/10.1371/journal.pone.0260819