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The Effects of a Multimodal Interventional Program on Cognitive Function, Instrumental Activities of Daily Living in Patients With Mild Alzheimer's Disease

복합중재 프로그램이 경도 알츠하이머병 치매환자의 인지기능 및 도구적 일상생활수행능력에 미치는 영향

  • Ham, Min-Joo (Dept. of Occupational Therapy, The Graduate School of Konyang University) ;
  • Kim, Su-Kyoung (Dept. of Occupational Therapy, Konyang University) ;
  • Yoo, Doo-han (Dept. of Occupational Therapy, Konyang University) ;
  • Lee, jae Shin (Dept. of Occupational Therapy, Konyang University)
  • 함민주 (건양대학교 일반대학원 작업치료학과) ;
  • 김수경 (건양대학교 의과학대학 작업치료학과) ;
  • 유두한 (건양대학교 의과학대학 작업치료학과) ;
  • 이재신 (건양대학교 의과학대학 작업치료학과)
  • Received : 2018.01.27
  • Accepted : 2018.03.14
  • Published : 2018.03.31

Abstract

Objective: This purpose of this study was to investigate the effects of a multimodal interventional program(MIP) that combined physical activity and emotional activities centering on cognitive activities on cognitive function, instrumental activities of daily living(IADL) in patients with mild Alzheimer's Disease. Methods: A total of 59 patients with mild Alzheimer's disease were randomly assigned to a study group of 39 patients and a control group of 20 patients. For the experimental group, the multimodal intervention program and the control group were applied for the non-intervention. MIP was conducted twice a week for 8 weeks and for 110 minutes per session. In order to evaluate the cognitive function of the subjects, MMSE-DS, COSAS were used, and K-IADL was used to measure IADL. Results: Among the 59 patients with mild Alzheimer's disease who were taking medication, the group with MIP showed a statistically significant improvement in cognitive function and instrumental activities of daily living compared with the group without non-intervention(p<.01). Conclusion: The multimodal intervention program is the effective intervention program for the maintenance and improvement of cognitive function and IADL in patient with mild Alzheimer's disease.

목적 : 본 연구는 경도 알츠하이머병 치매환자에게 인지활동을 중심으로 신체활동, 정서활동을 병행한 복합중재 프로그램을 적용하였을 시 대상자의 인지기능 및 도구적 일상생활수행능력에 미치는 영향을 알아보고자 하였다. 연구방법 : 약물치료 중인 경도 알츠하이머병 치매환자 59명을 실험군 39명, 대조군 20명으로 무작위 배정하였다. 실험군에는 복합중재 프로그램, 대조군은 비 중재를 적용하였다. 중재는 실험군에 8주 동안 주 2회, 회기 당 110분씩 총 16회기의 중재를 실시하였다. 중재 전 후 비교를 위하여 치매선별용 간이정신상태 검사(Mini-Mental State Examination for Dementia Screening; MMSE-DS), 노인용 전산화 인지평가도구(Computer Cognitive Senior Assessment System for Elderly; COSAS), 한국형 도구적 일상생활활동 측정도구(Korean Instrumental Activities of Daily Living; K-IADL)를 사용하였다. 결과 : 약물을 복용 중인 경도 알츠하이머병 치매환자 59명 중 복합중재 프로그램을 실시한 집단은 비 중재를 실시한 집단과 비교하여 인지기능과 도구적 일상생활수행능력이 통계적으로 유의미하게 향상되었다(p<.01). 결론 : 복합중재 프로그램은 경도 알츠하이머병 치매환자의 인지기능, 도구적 일상생활수행능력의 유지 및 향상에 효과적인 중재 프로그램임을 제시하였다.

Keywords

References

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