Journal of the Korean Medical Association (대한의사협회지)

Korean Medical Association (대한의사협회)
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Diagnosis and treatment of dry eye syndrome

안구건조증의 진단과 치료

  • Kim, Eun Chul (Department of Ophthalmology, Bucheon St. Mary's Hospital, The Catholic University of Korea College of Medicine)
  • 김은철 (가톨릭대학교 의과대학 부천성모병원 안과)
  • Received : 2018.05.09
  • Accepted : 2018.05.23
  • Published : 2018.06.30
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Abstract

Dry eye syndrome is a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film, and accompanied by ocular symptoms. Tear film instability and hyperosmolarity, ocular surface inflammation and damage, and neurosensory abnormalities play etiological roles. Symptom screening with the Five-item Dry Eye Questionnaire or Ocular Surface Disease Index can be used to identify the possibility that a patient might have DED dry eye syndrome and triggers. The results of these screening tools can lead to performing diagnostic tests of (ideally non-invasive) breakup time, osmolarity and ocular surface staining with fluorescein and lissamine green (observing the cornea, conjunctiva and eyelid margin). Meibomian gland dysfunction, lipid thickness/dynamics and assessments of the volume and severity of tear allow the subclassification of dry eye syndrome as predominantly evaporative or aqueous deficient, which informs the management of dry eye syndrome. A staged management algorithm was derived that presents a stepwise approach to implementing the various management and therapeutic options according to disease severity.

Keywords

References

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