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Genome sequence of Prevotella intermedia strain originally isolated from cervicofacial actinomycosis

경부안면형 방선균증에서 분리된 Prevotella intermedia의 유전체 염기서열 해독

  • Moon, Ji-Hoi (Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University) ;
  • Jang, Eun-Young (Department of Dentistry, Graduate School, Kyung Hee University) ;
  • Yang, Seok Bin (Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University) ;
  • Shin, Seung-Yun (Department of Periodontology, School of Dentistry, Kyung Hee University) ;
  • Ryu, Jae-In (Department of Preventive Dentistry, School of Dentistry, Kyung Hee University) ;
  • Lee, Jin-Yong (Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University) ;
  • Lee, Jae-Hyung (Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University)
  • 문지회 (경희대학교 치과대학 악안면생체공학교실) ;
  • 장은영 (경희대학교 대학원 치의학과) ;
  • 양석빈 (경희대학교 치과대학 악안면생체공학교실) ;
  • 신승윤 (경희대학교 치과대학 치주과학교실) ;
  • 류재인 (경희대학교 치과대학 예방치과학교실) ;
  • 이진용 (경희대학교 치과대학 악안면생체공학교실) ;
  • 이재형 (경희대학교 치과대학 악안면생체공학교실)
  • Received : 2018.11.27
  • Accepted : 2018.12.14
  • Published : 2019.03.31

Abstract

Anaerobic Gram-negative bacterium Prevotella intermedia is a part of normal flora of the oral cavity and associated with various types of oral and systemic diseases. We present here a draft genome sequence of P. intermedia ATCC 15032, originally isolated from cervicofacial actinomycosis. The genome is 2,848,426 bp in length and has a GC content of 43.45%. The genome includes 2,358 protein-coding genes, 5 rRNAs, and 43 tRNA. The sequence information will provide important clues in understanding the genome diversity within the bacterial species, and genetic basis for phenotypic differences among P. intermedia strains.

혐기성 그람 음성 세균인 Prevotella intermedia는 사람의 구강 내 정상세균총의 하나이고 다양한 구강 및 전신 질환과 관련이 있다. 본 논문에서는 경부안면형 방선균증으로부터 분리된 P. intermedia ATCC 15032 균주의 유전체 염기서열을 분석하여 보고한다. 이 균주의 유전체는 2,848,426 bp의 크기로 GC 함량은 43.45%이다. 이 유전체 서열 정보는 P. intermedia 종 내에서의 균주 간 유전체 다양성 및 표현형 차이의 유전적 기초를 이해하는데 중요한 정보를 제공할 것이다.

Keywords

MSMHBQ_2019_v55n1_58_f0001.png 이미지

Fig. 1. Comparison of genome sequences of 4 P. intermedia strains (using P. intermedia 17 as a reference genome) by the BLAST Ring Image Generator (BRIG) (Alikhan et al., 2011).

Table 1. Genome features of Prevotella intermedia ATCC 15032

MSMHBQ_2019_v55n1_58_t0001.png 이미지

References

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