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Pain perception and efficacy of local analgesia using 2% lignocaine, buffered lignocaine, and 4% articaine in pediatric dental procedures

  • Afsal, M.M (Department of Pedodontics and Preventive Dentistry, UCMS (University of Delhi) & GTB Hospital) ;
  • Khatri, Amit (Department of Pedodontics and Preventive Dentistry, UCMS (University of Delhi) & GTB Hospital) ;
  • Kalra, Namita (Department of Pedodontics and Preventive Dentistry, UCMS (University of Delhi) & GTB Hospital) ;
  • Tyagi, Rishi (Department of Pedodontics and Preventive Dentistry, UCMS (University of Delhi) & GTB Hospital) ;
  • Khandelwal, Deepak (Department of Pedodontics and Preventive Dentistry, UCMS (University of Delhi) & GTB Hospital)
  • Received : 2019.03.13
  • Accepted : 2019.04.10
  • Published : 2019.04.30

Abstract

Background: The purpose of this study was to compare the pain perception and anesthetic efficacy of 2% lignocaine with 1:200,000 epinephrine, buffered lignocaine, and 4% articaine with 1:200,000 epinephrine for the inferior alveolar nerve block. Methods: This was a double-blind crossover study involving 48 children aged 5-10 years, who received three inferior alveolar nerve block injections in three appointments scheduled one week apart from the next. Pain on injection was assessed using the Wong-Baker Faces pain scale and the sound eye motor scale (SEM). Efficacy of anesthesia was assessed by subjective (tingling or numbness of the lip, tongue, and corner of mouth) and objective signs (pain on probing). Results: Pain perception on injection assessed with Wong-Baker scale was significantly different between buffered lignocaine and lignocaine (P < 0.001) and between buffered lignocaine and articaine (P = 0.041). The onset of anesthesia was lowest for buffered lignocaine, with a statistically significant difference between buffered lignocaine and lignocaine (P < 0.001). Moreover, the efficacy of local analgesia assessed using objective signs was significantly different between buffered lignocaine and lignocaine (P < 0.001) and between lignocaine and articaine. Conclusion: Buffered lignocaine was the least painful and the most efficacious anesthetic agent during the inferior alveolar nerve block injection in 5-10-year-old patients.

Keywords

References

  1. Gorczyca R, Filip R, Walczak E. Psychological aspects of pain. Ann Agric Environ Med 2013; 20: 23-7.
  2. Malamed SF. Handbook of local anesthesia. 6th ed. St. Louis, Mo., USA: Mosby. 2012 58-63.
  3. Chopra R, Jindal G, Sachdev V, Sandhu M. Double-blind crossover study to compare pain experience during inferior alveolar nerve block administration using buffered two percent lidocaine in children. Pediatr Dent 2016; 38: 25-9.
  4. Ferger P, Marxkors R. A new anesthetic in dental prosthetics. Dtsch Zahnarztl Z 1973; 28: 87-9.
  5. Al-Samadani KH, Gazal G. Effectiveness of benzocaine in reducing deep cavity restoration and post-extraction stress in dental patients. Saudi Med J 2015; 36: 1342-7. https://doi.org/10.15537/smj.2015.11.12274
  6. Davoudi A, Rismanchian M, Akhavan A, Nosouhian S, Bajoghli F, Haghighat A, et al. A brief review on the efficacy of different possible and nonpharmacological techniques in eliminating discomfort of local anesthesia injection during dental procedures. Anesth Essays Res 2016; 10: 13-6. https://doi.org/10.4103/0259-1162.167846
  7. Gordon D, Heimberg RG, Tellez M, Ismail AI. A critical review of approaches to the treatment of dental anxiety in adults. J Anxiety Disord 2013; 27: 365-78. https://doi.org/10.1016/j.janxdis.2013.04.002
  8. Yuen HK, Wolf BJ, Bandyopadhyay D, Magruder KM, Selassie AW, Salinas CF. Factors that limit access to dental care for adults with spinal cord injury. Spec Care Dentist 2010; 30: 151-6. https://doi.org/10.1111/j.1754-4505.2010.00146.x
  9. Al-Melh MA, Andersson L. Comparison of topical anesthetics (EMLA/Oraqix vs. benzocaine) on pain experienced during palatal needle injection. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 103: e16-20. https://doi.org/10.1016/j.tripleo.2006.11.033
  10. Al-Melh MA, Andersson L. Reducing pain from palatal needle stick by topical anesthetics: a comparative study between two lidocaine/prilocaine substances. J Clin Dent 2008; 19: 43-7.
  11. Hogan ME, vanderVaart S, Perampaladas K, Machado M, Einarson TR, Taddio A. Systematic review and metaanalysis of the effect of warming local anesthetics on injection pain. Ann Emerg Med 2011; 58: 86-98.e1. https://doi.org/10.1016/j.annemergmed.2010.12.001
  12. Leaper D. Warming local anaesthetic prior to injection reduces injection pain. Evid Based Med 2012; 17: 46-7. https://doi.org/10.1136/ebm.2011.100165
  13. Conway CM, Ellis DB, King NW. A comparison of the acute hemodynamic effects of thiopentone, methohexitone and propanidid in the dog. Br J Anaesth 1968; 40: 736-45. https://doi.org/10.1093/bja/40.10.736
  14. Wright GZ, Weinberger SJ, Marti R, Plotzke O. The effectiveness of infiltration anesthesia in the mandibular primary molar region. Pediatr Dent 1991; 13: 278-83.
  15. Wong DL, Baker CM. Pain in children: comparison of assessment scales. Pediatr Nurs 1988; 14: 9-17.
  16. Steele EA, Ng JD, Poissant TM, Campbell NM. Comparison of injection pain of articaine and lidocaine in eyelid surgery. Ophthalmic Plast Reconstr Surg 2009; 25: 13-5. https://doi.org/10.1097/IOP.0b013e3181912016
  17. Costa RSM, Ribeiro SN, Cabral ED. Determinants of painful experience during dental treatment. Rev Dor. Sao Paulo 2012; 13: 365-70.
  18. Shehab LA, Basheer B, Baroudi K. Effectiveness of lidocaine Denti $patch^{(R)}$ system versus lidocaine gel as topical anesthetic agent in children. J Indian Soc Pedod Prev Dent 2015; 33: 285-90. https://doi.org/10.4103/0970-4388.165664
  19. Malamed SF, Gagnon S, Leblanc D. A comparison between articaine HCl and lidocaine HCl in pediatric dental patients. Pediatr Dent 2000; 22: 307-11.
  20. Kashyap VM, Desai R, Reddy PB, Menon S. Effect of alkalinisation of lignocaine for intraoral nerve block on pain during injection and speed of onset of anesthesia. Br J Oral Maxillofac Surg 2011; 49: e72-75. https://doi.org/10.1016/j.bjoms.2011.04.068
  21. Sumer M, Misir F, Celebi N, Mugalai M. A comparison of injection pain with articaine with adrenaline, prilocaine with phenylpressin and lidocaine with adrenaline. Med Oral Patol Oral Cir Bucal 2008; 13: E427-30.
  22. Whitcomb M, Drum M, Reader A, Nusstein J, Beck M. A prospective, randomized, double-blind study of the anesthetic efficacy of sodium bicarbonate buffered 2% lidocaine with 1:100,000 epinephrine in inferior alveolar nerve blocks. Anesth Prog 2010; 57: 59-66. https://doi.org/10.2344/0003-3006-57.2.59
  23. Hobeich P, Simon S, Schneiderman E, He J. A prospective, randomized, double-blind comparison of the injection pain and anesthetic onset of 2% lidocaine with 1:100,000 epinephrine buffered with 5% and 10% sodium bicarbonate in maxillary infiltrations. J Endod 2013; 39: 597-9. https://doi.org/10.1016/j.joen.2013.01.008
  24. Chow MY, Sia AT, Koay CK, Chan YW. Alkalinization of lidocaine does not hasten the onset of axillary brachial plexus block. Anesth Analg 1998; 86: 566-8. https://doi.org/10.1213/00000539-199803000-00024
  25. Saraf SP, Saraf PA, Kamatagi K, Hugar S, Tagmond S, Patil J. A comparative evaluation of anesthetic efficacy of articaine 4% and lidocaine 2% with anterior middle superior alveolar nerve block and infraorbital nerve block: An in vivo study. J Conserv Dent 2016; 19: 527-31. https://doi.org/10.4103/0972-0707.194021
  26. Kambalimath DH, Dolas RS, Kambalimath HV, Agarwal MS. Efficacy of 4% articaine and 2% lidocaine: a clinical study. J Maxillofac Oral Surg 2013; 12: 3-10. https://doi.org/10.1007/s12663-012-0368-4

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