Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지
DOI QR코드

DOI QR Code

Systematic Review of Acupuncture Treatment for Mild Cognitive Impairment

  • Kim, Min Wook (Department of Acupuncture and Moxibustion Medicine, DongShin University) ;
  • Yoo, Jae Hee (Department of Acupuncture and Moxibustion Medicine, DongShin University) ;
  • Go, Hong Je (Department of Acupuncture and Moxibustion Medicine, DongShin University) ;
  • Kim, Seon Woo (Department of Acupuncture and Moxibustion Medicine, Gwang-ju Jaseng Hospital of Oriental Medicine) ;
  • Jang, Seung Won (Department of Acupuncture and Moxibustion Medicine, DongShin Korean Medicine Hospital) ;
  • Jeong, Hyun Jin (Department of Oriental Internal Medicine, DongShin University Oriental Hospital) ;
  • Kim, Jae Hong (Department of Acupuncture and Moxibustion Medicine, DongShin University)
  • Received : 2019.04.27
  • Accepted : 2019.05.03
  • Published : 2019.05.30
Download PDF
⟨ Previous Next ⟩

Abstract

Background: The aim of this study was to review clinical efficacy of acupuncture treatment of mild cognitive impairment. Methods: Randomized controlled trials that performed acupuncture treatment for mild cognitive impairment were retrieved from 6 online databases (PubMed, Cochrane Library, EMBASE, CNKI, NDSL, OASIS) on September $30^{th}$, 2018. Studies were selected according to inclusion and exclusion criteria, and were reviewed by Risk of Bias assessment. Results: In total, 21 studies were included in this review. All studies were Chinese (19 studies published in Chinese and 2 in English). The sample size, 50 to 100, and the number of treatment times, 20 to 30, were the largest range in all studies. The most treatments performed was 30. The longest treatment period was 56 days, which accounted for 33% of the studies. The most frequently used evaluation index was the Mini Mental State Examination followed by the Montreal Cognitive Assessment, each used 17 times and 15 times, respectively. The most frequently used acupoints were GV20, EX-HN1, GB20, and GV24, which accounted for 47% of total number of acupoints used. In 48% of the studies, needle retention time was 30 minutes. Western medicine treatment was the most common control group. Most studies reported that the intervention group was statistically significantly different to the control group. Conclusion: These results suggest that acupuncture for mild cognitive impairment was effective. However, it is difficult to confirm this conclusion because the quality of most of these studies were of low quality.

Keywords

References

  1. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 1999;56:303-308. https://doi.org/10.1001/archneur.56.3.303
  2. Xiao L, Shang HC, Wang JY, Hu J, Xiong J. Assessing the Quality of Reports about Randomized Controlled Trials of Acupuncture Treatment on Mild Cognitive Impairment. PLoS ONE 2011;6:1-6.
  3. Gmdman M, Petemen RC, Morris JC. Rate of dementia of the Alzheimer type in patients with mild cognitive impairment. Neurology 1996;46:A403.
  4. Doody RS, Ferris SH, Salloway S, Sun Y, Goldman R, Watkins WE et al. Donepezil treatment of patients with MCI: a 48-week randomized, placebocontrolled trial. Neurology 2009;72:1555-1561. https://doi.org/10.1212/01.wnl.0000344650.95823.03
  5. Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S et al. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med 2005;352:2379-2388. https://doi.org/10.1056/NEJMoa050151
  6. Salloway S, Ferris S, Kluger A, Goldman R, Griesing T, Kumar D et al. Efficacy of donepezil in mild cognitive impairment: a randomized placebocontrolled trial. Neurology 2004;63:651-657. https://doi.org/10.1212/01.WNL.0000134664.80320.92
  7. Petersen RC, Caracciolo B, Brayne C, Gauthier S, Jelic V, Fratiglioni L. Mild cognitive impairment: a concept in evolution. J Intern Med 2014;275:214-228. https://doi.org/10.1111/joim.12190
  8. Simon SS, Yokomizo JE, Bottino CMC. Cognitive intervention in amnestic Mild Cognitive Impairment: a systematic review. Neurosci Biobehav Rev 2012;36(4):1163-1178. https://doi.org/10.1016/j.neubiorev.2012.01.007
  9. Song HJ, Cho MR. The Effects of Acupuncture at Sobu (HT8) and Haenggan (LR2) on Scopolamine-induced Cognitive Impairment in Rat Model. J Acupunct Res 2018;35:28-36. [in Korean]. https://doi.org/10.13045/jar.2018.00038
  10. Hyun MK, Mo MJ, Hwang DR, Yang TJ, Lee JH, Lee EJ et al. The Effects of Jodeungsan Pharmacopuncture at GB20 on Cognitive Impairment Induced by Focal Brain Injury in Rats. J Acupunct Res 2016;33:49-63. [in Korean]. https://doi.org/10.13045/acupunct.2016054
  11. Liu J, Liu ZY. Clinical Observations on Electroacupuncture Treatment for Mild Cognitive Impairment of Kidney Essence Deficiency Type. Shanghai J Acupunct Moxibustion 2009;28:319-321. [in Chinese].
  12. Sun YZ, Zhang Y. Clinical Observations on the Treatment of Mild Cognitive Impairment in Elder People by Combined Acupuncture and Duxil. J Clin Acupunct Moxibustion 2009;25:16-17. [in Chinese].
  13. Wang QD [Dissertation]. Clinical study of jiannao bushen acupuncture for MCI. Harbin (China) : Heilongjiang University of Chinese Medicine; 2009. [in Chinese].
  14. Zhang Y [Dissertation]. Observing the efficacy of the combination of acupuncture and duxil in treating mild cognitive impairment. Harbin (China): Heilongjiang University of Chinese Medicine; 2009. [in Chinese].
  15. Jin XZ [Dissertation]. Electro-acupuncture intervention in essence deficiency Mild Cognitive Impairment study of Clinical. Urumqi (China): Xinjiang medical university; 2010. [in Chinese].
  16. Liu XP [Dissertation]. Electro-acupuncture intervention in essence deficiency Mild Cognitive Impairment Study of H-MRS. Urumqi (China): Xinjiang medical university; 2010. [in Chinese].
  17. Wang Y, Cao H, Xing Y. Observation of Effect of Cluster Needling of Electro-'qi'acupuncture Combination of Cognitive Training in Acupuncture treatment of Mild Cognitive Impairment. J Clin Acupunct Moxibustion 2010;26:32-34. [in Chinese].
  18. Wang Y [Dissertation]. Observation of Effect of Cluster Needling of Electro-'qi'acupuncture Combination of Cognitive Training in Acupuncture treatment of Mild Cognitive Impairment. Harbin (China): Heilongjiang University of Chinese Medicine; 2010. [in Chinese].
  19. Yu T [Dissertation]. Randomized controlled clinical study of "Dredge Du Channel and Regulate Marrow" with Electric Acupuncture on Mild Cognitive Impairment. Chengdu (China): Chengdu University of Traditional Chinese Medicine; 2010. [in Chinese].
  20. Chen ZG [Dissertation]. A Multicenter Randomized Controlled Trial on Treatment of Mild Cognitive Impairment by Electric Scalp Acupuncture. Chengdu (China): Chengdu University of Traditional Chinese Medicine; 2011. [in Chinese].
  21. Li KS [Dissertation]. Clinical Observation on the Treatment of Mild Cognitive Impairment by Combined Acupuncture and Medication. Harbin (China): Heilongjiang University of Chinese Medicine; 2011. [in Chinese].
  22. Li MP [Dissertation]. Clinical Observation on the Treatment of Mild Cognitive Impairment by Combined Acupuncture and Yizhiyin. Harbin (China): Heilongjiang University of Chinese Medicine; 2012. [in Chinese].
  23. Zhang ZJ, Yuan WQ, Zhang JY, Zhang YF, Li JM, Tian HJ et al. Clinical Observation on the Treatment of Mild Cognitive Impairment by Combined Acupuncture and Nimodipine, Naoxingtong Capsules. Med Innov Chin 2012;9:40-41. [in Chinese].
  24. Zhao Y. Efficacy of Acupuncture Combined with Nimodipine in the Treatment of Mild Cognitive Impairment. Chin J Clin Ration Drug Use 2012;5:16-17. [in Chinese].
  25. Zhang H, Zhao L, Yang S, Chen ZG, Li YK, Peng XH et al. Clinical observation on effect of scalp electroacupuncture for mild cognitive impairment. J Tradit Chin Med 2013;33:46-50. https://doi.org/10.1016/S0254-6272(13)60099-0
  26. Du L [Dissertation]. Study of Tongdu Tiaoshen Acupuncture on Mild Cognitive Impairment Patients with Serum BDNF Effect. Hefei (China): Anhui University of Chinese Medicine; 2015. [in Chinese].
  27. Wang J, Li X, Xia DJ. Clinical Observation on Treatment of Mild Cognitive Impairment by Acupuncture Combined with Jiangzhi Yizhi Granule. Zhejiang J Integr Tradit Chin West Med 2015;25:908-911. [in Chinese].
  28. Li X [Dissertation]. Clinical Observation on the Treatmnet of Mild Cognitive Impairment by combined Acupuncture and Jiangzhi Yizhi granule. Hangzhou (China): Zhejiang Chinese Medical University; 2016. [in Chinese].
  29. Chen J [Dissertation]. Clinical Observation on the Five Elements of Acupuncture in the Treatment of the Patients with Mild Cognitive Impairment. Nanning (China): Guangxi Traditional Chinese Medical University; 2017. [in Chinese].
  30. Liu L [Dissertation]. Clinical Observation on Herapeutic effect of Mild Cognitive Impairment by Yu style Cluster Acupuncture. Harbin (China): Heilongjiang University of Chinese Medicine; 2017. [in Chinese].
  31. Tan TT, Wang D, Huang JK, Zhou XM, Yuan X, Liang JP et al. Modulatory effects of acupuncture on brain networks in mild cognitive impairment patients. Neural Regen Res 2017;12:250-258. https://doi.org/10.4103/1673-5374.200808
  32. Hu J, Zhang N, Wang ZX, Liang YW, Qian Q. Systematic review of acupuncture in treating mild cognitive impairment. Chin J Ethnomed Ethnopharma 2014;12:17-21. [in Chinese].
  33. Mai W, Zheng JH. Clinical Efficacy of Scalp Acupuncture on Mild Cognitive Impairment: A Meta-analysis Study. J Liaoning University Tradit Chin Med 2015;17:121-124. [in Chinese].
  34. Wang Y [Dissertation]. The Study of Minimum Mental State Examination, blood lipid and the Analysis of Acupuncture and Moxibustion Treatment of MCI. Nanning (China): Guangxi Traditional Chinese Medical University; 2017. [in Chinese].
  35. Higgins JPT, Green S, editors. Cochrane handbook for systematic reviews of interventions Version 5.1.0. Chichester (UK): John Wiley & Sons, Ltd; 2011.
  36. Schulz KF, Altman DG, Moher D. CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomized Trials. Int J Surg 2011;9:672-677. https://doi.org/10.1016/j.ijsu.2011.09.004

Cited by

  1. Corrigendum to "Systematic Review of Acupuncture Treatment for Mild Cognitive"[J Acupunct Res 2019;36(2):72-79] vol.36, pp.4, 2019, https://doi.org/10.13045/jar.2019.00108.e1
  2. Feasibility and Effect of Electroacupuncture on Cognitive Function Domains in Patients with Mild Cognitive Impairment: A Pilot Exploratory Randomized Controlled Trial vol.11, pp.6, 2019, https://doi.org/10.3390/brainsci11060756