Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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Epidemiological and Clinical Characteristics of Confirmed Cases of Severe Fever With Thrombocytopenia Syndrome in Jeju Province, Korea, 2014-2018

  • Kim, Jinhee (Jeju Center for Infectious Diseases Control and Prevention) ;
  • Bae, Jong-Myon (Jeju Center for Infectious Diseases Control and Prevention)
  • Received : 2018.12.13
  • Accepted : 2019.04.02
  • Published : 2019.05.31
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Abstract

Objectives: Jeju Province is well known as the region showing the highest incidence of severe fever with thrombocytopenia syndrome (SFTS) in South Korea. The aim of this study was to evaluate the epidemiological and clinical characteristics of SFTS patients in Jeju Province. Methods: The primary data for this study were obtained from the Integrated Diseases and Health Control System of the Korea Centers for Disease Control and Prevention (KCDCIS). The selection criteria were confirmed cases of SFTS with a residence listed in Jeju Province at the time of diagnosis, reported to the KCDCIS between July 16, 2014 and November 30, 2018. Results: Of 55 confirmed cases of SFTS, the case fatality rate was 10.9% (95% confidence interval [CI], 4.1 to 22.2). The most common presenting symptoms at diagnosis of severe fever, myalgia, and diarrhea had incidences of 83.6% (95% Cl, 71.2 to 92.2), 45.5% (95% Cl, 32.0 to 59.5), and 40.0% (95% CI, 27.0 to 54.1), respectively. Conclusions: Compared to SFTS patients nationwide in 2013-2015, the subjects of this study exhibited a lower case fatality rate and had a lower incidence of severe fever, myalgia, and confusion.

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References

  1. Robles NJ, Han HJ, Park SJ, Choi YK. Epidemiology of severe fever and thrombocytopenia syndrome virus infection and the need for therapeutics for the prevention. Clin Exp Vaccine Res 2018;7(1):43-50. https://doi.org/10.7774/cevr.2018.7.1.43
  2. Yu XJ, Liang MF, Zhang SY, Liu Y, Li JD, Sun YL, et al. Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med 2011;364(16):1523-1532. https://doi.org/10.1056/NEJMoa1010095
  3. Bae JM. Differences of clinical manifestation of severe fever with thrombocytopenia syndrome between Korean and Chinese patients. J Korean Soc Emerg Med 2019;30(3) (in press).
  4. Guo CT, Lu QB, Ding SJ, Hu CY, Hu JG, Wo Y, et al. Epidemiological and clinical characteristics of severe fever with thrombocytopenia syndrome (SFTS) in China: an integrated data analysis. Epidemiol Infect 2016;144(6):1345-1354. https://doi.org/10.1017/S0950268815002678
  5. Choi SJ, Park SW, Bae IG, Kim SH, Ryu SY, Kim HA, et al. Severe fever with thrombocytopenia syndrome in South Korea, 2013-2015. PLoS Negl Trop Dis 2016;10(12):e0005264. https://doi.org/10.1371/journal.pntd.0005264
  6. Bae JM. Epidemiological characteristics of scrub typhus on the Jeju Island. Epidemiol Health 2017;39:e2017060. https://doi.org/10.4178/epih.e2017060
  7. Jeju Special Self-Governing Province. Report of second infection on severe fever and thrombocytopenia syndrome [cited 2018 Dec 13]. Available from: https://www.jeju.go.kr/news/bodo/list.htm;jsessionid=GJjkn12worQo605EqLshkscdkgCO570pLYkeOpjw3K9YiqI80kfrH8yT2dBCCDaz.was2_servlet_engine6?category=84&_layout=playout&_view=print&page=3&act=view&seq=1120332 (Korean).

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