Asian-Australasian Journal of Animal Sciences

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
권호 표지
DOI QR코드

DOI QR Code

Oxidative stress status and reproductive performance of sows during gestation and lactation under different thermal environments

  • Zhao, Yan (Department of Animal Science and Technology, Shanxi Agricultural University) ;
  • Kim, Sung Woo (Department of Animal Science, North Carolina State University)
  • Received : 2019.04.23
  • Accepted : 2019.09.18
  • Published : 2020.05.01
Download PDF
⟨ Previous Next ⟩

Abstract

Objective: Two experiments were conducted using 28 healthy multiparous sows to evaluate the oxidative stress status and reproductive performance of sows during gestation and lactation under different thermal environments. Methods: Fourteen multiparous sows were used in Exp. 1 under a high thermal environment, and the other 14 multiparous sows were used in Exp. 2 under a moderate thermal environment. In both experiments, reproductive performances of sows were recorded. Plasma samples were collected on d 35, 60, 90, and 109 of gestation, and d 1 and 18 of lactation for malondialdehyde, protein carbonyls, 8-hydroxy-deoxyguanosine, immunoglobulin g (IgG), and IgM analysis. Results: For sows in Exp. 1, plasma malondialdehyde concentration on d 109 of gestation tended to be greater (p<0.05) than it on d 18 of lactation. Plasma concentration of protein carbonyl on d 109 of gestation was the greatest (p<0.05) compared with all the other days. Plasma concentrations of 8-hydroxy-deoxyguanosine on d 109 of gestation was greater (p<0.05) than d 18 of lactation in Exp. 1. For sows in Exp. 2, there was no difference of malondialdehyde and protein carbonyl concentration during gestation and lactation. In both Exp. 1 and 2, litter size and litter weight were found to be negatively correlated with oxidative stress indicators. Conclusion: Sows under a high thermal environment had increased oxidative stress during late gestation indicating that increased oxidative damage to lipid, protein, and DNA could be one of the contributing factors for reduced reproductive performance of sows in this environment. This study indicates the importance of providing a moderate thermal environment to gestating and lactating sows to minimize the increase of oxidative stress during late gestation which can impair reproductive outcomes.

Keywords

References

  1. Betteridge DJ. What is oxidative stress? Metabolism 2000;49:3-8. https://doi.org/10.1016/S0026-0495(00)80077-3
  2. Gutteridge JM. Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin Chem 1995;41:1819-28. https://doi.org/10.1093/clinchem/41.12.1819
  3. Hall ED. Efficacy and mechanisms of action of the cytoprotective lipid peroxidation inhibitor tirilazad mesylate in subarachnoid haemorrhage. Eur J Anaesthesiol 1996;13:279-89. https://doi.org/10.1046/j.1365-2346.1996.00980.x
  4. Bottje WG, Wang S, Kelly FJ, Dunster C, Williams A, Mudway I. Antioxidant defenses in lung lining fluid of broilers: impact of poor ventilation conditions. Poult Sci 1998;77:516-22. https://doi.org/10.1093/ps/77.4.516
  5. Zhao Y, Flowers B, Saraiva A, Yeum KJ, Kim SW. Effect of social ranks and gestation housing systems on oxidative stress status, reproductive performance, and immune status of sows. J Anim Sci 2014;91:5848-58. https://doi.org/10.2527/jas.2013-6388
  6. Renaudeau D, Noblet J. Effects of exposure to high ambient temperature and dietary protein level on sow milk production and performance of piglets. J Anim Sci 2001;79:1540-8. https://doi.org/10.2527/2001.7961540x
  7. Black JL, Mullan BP, Lorschy ML, Giles LR. Lactation in the sow during heat stress. Livest Prod Sci 1993;35:153-170. https://doi.org/10.1016/0301-6226(93)90188-N
  8. Renaudeau D, Quiniou N, Noblet J. Effects of exposure to high ambient temperature and dietary protein level on performance of multiparous lactating sows. J Anim Sci 2001;79:1240-9. https://doi.org/10.2527/2001.7951240x
  9. Flowers B, Day BN. Alterations in gonadotropin secretion and ovarian function in prepubertal gilts by elevated environmental temperature. Biol Reprod 1990;42:465-71. https://doi.org/10.1095/biolreprod42.3.465
  10. Zhang H, Wang Z, Liu G, He J, Su C. Effect of dietary fat supplementation on milk components and blood parameters of early-lactating cows under heat stress. Slovak J Anim Sci 2011;44:52-8.
  11. Wegner K, Lambertz C, Das G, Reiner G, Gauly M. Climatic effects on sow fertility and piglet survival under influence of a moderate climate. Animal 2014;8:1526-33. https://doi.org/10.1017/S1751731114001219
  12. Ji F, Wu G, Blanton JR, Kim SW. Weight and compositional changes in pregnant gilts and its implication to nutrition. J Anim Sci 2005;83:366-75. https://doi.org/10.2527/2005.832366x
  13. Kim SW, Wu G. Regulatory role for amino acids in mammary gland growth and milk synthesis. Amino Acids 2009;37:89-95. https://doi.org/10.1007/s00726-008-0151-5
  14. Berchieri-Ronchi CB, Kim SW, Zhao Y, Correa CR, Yeum KJ, Ferreira ALA. Oxidative stress status of highly prolific sows during gestation and lactation. Animal 2011;5:1774-9. https://doi.org/10.1017/S1751731111000772
  15. Committee on Nutrient Requirements of Swine, National Research Council. Nutrient requirements of swine. 11th ed. Washington, DC, USA: National Academy Press; 2012.
  16. Shen YB, Weaver AC, Kim SW. Effect of feed grade L-methionine on growth performance and gut health in nursery pigs compared with conventional DL-methionine. J Anim Sci 2014;92:5530-9. https://doi.org/10.2527/jas.2014-7830
  17. Weaver AC, Kim SW. Supplemental nucleotides high in inosine 5-monophosphate to improve the growth and health of nursery pigs. J Anim Sci 2014;92:645-51. https://doi.org/10.2527/jas.2013-6564
  18. Chaytor AC, See MT, Hansen JA, de Souza ALP, Middleton TF, Kim SW. Effects of chronic exposure of diets with reduced concentrations of aflatoxin and deoxynivalenol on growth and immune status of pigs. J Anim Sci 2011;89:124-35. https://doi.org/10.2527/jas.2010-3005
  19. Huynh TTT, Aarnink AJA, Verstegen MWA, et al. Effects of increasing temperatures on physiological changes in pigs at different relative humidities. J Anim Sci 2005;83:1385-96. https://doi.org/10.2527/2005.8361385x
  20. Botto L, Lendelova J, Strmenova A, Reichstadterova T. The effect of evaporative cooling on climatic parameters in a stable for sows. Res Agric Eng 2014;60:S85-91. https://doi.org/10.17221/40/2013-RAE
  21. Seedorf J, Hartung J, Schroder M, et al. Temperature and moisture conditions in livestock buildings in Northern Europe. J Agric Eng Res 1998;70:49-57. https://doi.org/10.1006/jaer.1997.0284
  22. Britt JH, Szarek VE, Levis DG. Characterization of summer infertility of sows in large confinement units. Theriogenology 1983;20:133-40. https://doi.org/10.1016/0093-691X(83) 90032-8
  23. Robertshaw D. The environmental physiology of animal production. In: Clark JA, editor. Environmental aspects of housing for animal production. London, UK: Butterworths; 1981. p. 3-17.
  24. Ozawa M, Hirabayashi M, Kanai Y. Developmental competence and oxidative state of mouse zygotes heat-stressed maternally or in vitro. Reproduction 2002;124:683-9. https://doi.org/10.1530/rep.0.1240683
  25. Matsuzuka T, Ozawa M, Nakamura A, Ushitani A, Hirabayashi M, Kanai Y. Effects of heat stress on the redox status in the oviduct and early embryonic development in mice. J Reprod Dev 2005;51:281-7. https://doi.org/10.1262/jrd.16089
  26. Mujahid A, Akiba Y, Toyomizu M. Acute heat stress induces oxidative stress and decreases adaptation in young white leghorn cockerels by downregulation of avian uncoupling protein. Poult Sci 2007;86:364-71. https://doi.org/10.1093/ps/86.2.364
  27. Mujahid A, Akiba Y, Warden CH, Toyomizu M. Sequential changes in superoxide production, anion carriers and substrate oxidation in skeletal muscle mitochondria of heat-stressed chickens. FEBS Lett 2007;581:3461-7. https://doi.org/10.1016/ j.febslet.2007.06.051
  28. Karowicz-Bilinska A, Suzin J, Sieroszewski P. Evaluation of oxidative stress indices during treatment in pregnant women with intrauterine growth retardation. Med Sci Monit 2002;8:CR211-6.
  29. Toy H, Camuzcuoglu H, Arioz DT, Kurt S, Celik H, Aksoy N. Serum prolidase activity and oxidative stress markers in pregnancies with intrauterine growth restricted infants. J Obstet Gynaecol Res 2009;35:1047-53. https://doi.org/10.1111/j.1447-0756.2009.01063.x
  30. McGlone JJ, Von Borell EH, Deen J, et al. Reviews: Compilation of the scientific literature comparing housing systems for gestating sows and gilts using measures of physiology, behavior, performance, and health. Prof Anim Sci 2004;20:105-17. https://doi.org/10.15232/S1080-7446(15)31285-7

Cited by

  1. Effects of supplemental xylanase on health of the small intestine in nursery pigs fed diets with corn distillers’ dried grains with solubles vol.98, pp.6, 2020, https://doi.org/10.1093/jas/skaa185
  2. Understanding intestinal health in nursery pigs and the relevant nutritional strategies vol.34, pp.3, 2021, https://doi.org/10.5713/ab.21.0010
  3. Investigation of the efficacy of mycotoxin-detoxifying additive on health and growth of newly-weaned pigs under deoxynivalenol challenges vol.34, pp.3, 2020, https://doi.org/10.5713/ajas.20.0567
  4. Effects of dietary supplementation of nucleotides from late gestation to lactation on the performance and oxidative stress status of sows and their offspring vol.7, pp.1, 2020, https://doi.org/10.1016/j.aninu.2020.10.004
  5. Physiological Effects of Deoxynivalenol from Naturally Contaminated Corn on Cerebral Tryptophan Metabolism, Behavioral Response, Gastrointestinal Immune Status and Health in Pigs Following a Pair-Feed vol.13, pp.6, 2020, https://doi.org/10.3390/toxins13060393
  6. Nutritional and functional values of lysed Corynebacterium glutamicum cell mass for intestinal health and growth of nursery pigs vol.99, pp.12, 2021, https://doi.org/10.1093/jas/skab331