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Electroacupuncture for Women with Overactive Bladder: A Systematic Review and Meta-analysis of Randomized Controlled Trials

여성 과민성 방광 전침 치료의 무작위 대조군 연구에 관한 체계적 문헌 고찰

  • Ha, Su-Jin (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Hwang, Deok-Sang (Dept. of Korean Medicine Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Jin-Moo (Dept. of Korean Medicine Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Chang-Hoon (Dept. of Korean Medicine Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Jang, Jun-Bock (Dept. of Korean Medicine Gynecology, College of Korean Medicine, Kyung Hee University)
  • 하수진 (경희대학교 대학원 임상한의학과) ;
  • 황덕상 (경희대학교 한의과대학 한방부인과교실) ;
  • 이진무 (경희대학교 한의과대학 한방부인과교실) ;
  • 이창훈 (경희대학교 한의과대학 한방부인과교실) ;
  • 장준복 (경희대학교 한의과대학 한방부인과교실)
  • Received : 2020.07.11
  • Accepted : 2020.08.28
  • Published : 2020.08.28

Abstract

Objectives: The purpose of this study is to assess the efficacy and safety of electroacupuncture for women with overactive bladder (OAB) comparing with sham- acupuncture, and electroacupuncture plus drugs. Methods: We searched 8 databases upto May 26, 2020. Randomised controlled trials (RCTs) were eligible. The risk of bias was assessed by two independent authors using the Cochrane risk of bias tool. Study outcomes were calculated by standardized mean differences (SMD) with 95% confidence intervals (Cls) and mean differences (MD) with 95% Cls. Results: Of 146 screened, 5 RCTs were included. Number of participants per study ranged from 5 to 57. The combined results showed that electroacupuncture (EA) may be more effective than sham acupuncture or enhance solifenacin succinates in improving Overactive Bladder Symptom Score (OABSS) and urination frequency of 24 h. However, more trials with high quality and larger sample sizes will be needed to provide sufficient evidence. Only 5 of 187 OAB patients from the included studies reported mild adverse reactions related to EA, therefore, electroacupuncture is safe for treating OAB. Conclusions: Electroacupuncture might have effect in decreasing urination frequency of 24 h and OABSS. However, the evidences ins in sufficient to show the effect using electroacupuncture alone or additional effect to drugs in treating OAB.

Keywords

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