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Control measures to African swine fever outbreak: active response in South Korea, preparation for the future, and cooperation

  • Kim, Yong-Joo (Foreign Animal Disease Division, Animal and Plant Quarantine Agency) ;
  • Park, Bongkyun (Foreign Animal Disease Division, Animal and Plant Quarantine Agency) ;
  • Kang, Hae-Eun (Foreign Animal Disease Division, Animal and Plant Quarantine Agency)
  • Received : 2020.09.16
  • Accepted : 2020.12.13
  • Published : 2021.01.31

Abstract

African swine fever (ASF) is one of the most complex infectious swine diseases and the greatest concern to the pig industry owing to its high mortality and no effective vaccines available to prevent the disease. Since the first outbreak of ASF in pig farms, ASF has been identified in 14 pig farms in four cities/counties in South Korea. The outbreak was resolved in a short period because of the immediate control measures and cooperative efforts. This paper reviews the ASF outbreak and the experience of successfully stopping ASF in pig farms in South Korea through active responses to prevent the spread of ASF. In addition, suitable changes to build a sustainable pig production system and collaborative efforts to overcome the dangerous animal disease, such as ASF, are discussed.

Keywords

Acknowledgement

This study was supported by a grant from the Animal and Plant Quarantine Agency (Grant No. B-1543085-2020-22-01), the Ministry of Agriculture, Food and Rural Affairs, Republic of Korea.

References

  1. Montgomery RE. On a form of swine fever occurring in British East Africa (Kenya Colony). J Comp Pathol Ther. 1921;34:159-191. https://doi.org/10.1016/s0368-1742(21)80031-4
  2. VanderWaal K, Deen J. Global trends in infectious diseases of swine. Proc Natl Acad Sci U S A. 2018;115(45):11495-11500. https://doi.org/10.1073/pnas.1806068115
  3. Alonso C, Borca M, Dixon L, Revilla Y, Rodriguez F, Escribano JM; Ictv Report Consortium. ICTV virus taxonomy profile: Asfarviridae. J Gen Virol. 2018;99(5):613-614. https://doi.org/10.1099/jgv.0.001049
  4. Probst C, Globig A, Knoll B, Conraths FJ, Depner K. Behaviour of free ranging wild boar towards their dead fellows: potential implications for the transmission of African swine fever. R Soc Open Sci. 2017;4(5):170054. https://doi.org/10.1098/rsos.170054
  5. Sanchez-Cordon PJ, Montoya M, Reis AL, Dixon LK. African swine fever: a re-emerging viral disease threatening the global pig industry. Vet J. 2018;233:41-48. https://doi.org/10.1016/j.tvjl.2017.12.025
  6. Chenais E, Depner K, Guberti V, Dietze K, Viltrop A, Stahl K. Epidemiological considerations on African swine fever in Europe 2014-2018. Porcine Health Manag. 2019;5(1):6. https://doi.org/10.1186/s40813-018-0109-2
  7. Zhou X, Li N, Luo Y, Liu Y, Miao F, Chen T, et al. Emergence of African swine Fever in China, 2018. Transbound Emerg Dis. 2018;65(6):1482-1484. https://doi.org/10.1111/tbed.12989
  8. ASF Situation in Asia Update [Internet]. Rome: FAO; http://www.fao.org/ag/againfo/programmes/en/empares/ASF/2020/Situation_update_2020_03_05.html. Updated 2020.
  9. Situational Updates of ASF in Asia and the Pacific [Internet]. Paris: OIE; http://rr-asia.oie.int/en/projects/asf/situational-updates-of-asf/. Updated 2020.
  10. Kim HJ, Cho KH, Lee SK, Kim DY, Nah JJ, Kim HJ, et al. Outbreak of African swine fever in South Korea, 2019. Transbound Emerg Dis. 2020;67(2):473-475. https://doi.org/10.1111/tbed.13483
  11. Jo YS, Gortazar C. African swine fever in wild boar, South Korea, 2019. Transbound Emerg Dis. Forthcoming 2020.
  12. Galindo I, Alonso C. African swine fever virus: a review. Viruses. 2017;9(5):103. https://doi.org/10.3390/v9050103
  13. Dixon LK, Chapman DA, Netherton CL, Upton C. African swine fever virus replication and genomics. Virus Res. 2013;173(1):3-14. https://doi.org/10.1016/j.virusres.2012.10.020
  14. Bastos AD, Penrith ML, Cruciere C, Edrich JL, Hutchings G, Roger F, et al. Genotyping field strains of African swine fever virus by partial p72 gene characterisation. Arch Virol. 2003;148(4):693-706. https://doi.org/10.1007/s00705-002-0946-8
  15. Achenbach JE, Gallardo C, Nieto-Pelegrin E, Rivera-Arroyo B, Degefa-Negi T, Arias M, et al. Identification of a new genotype of african swine fever virus in domestic pigs from Ethiopia. Transbound Emerg Dis. 2017;64(5):1393-1404. https://doi.org/10.1111/tbed.12511
  16. Yoo D, Kim H, Lee JY, Yoo HS. African swine fever: etiology, epidemiological status in Korea, and perspective on control. J Vet Sci. 2020;21(2):e38. https://doi.org/10.4142/jvs.2020.21.e38
  17. Guinat C, Reis AL, Netherton CL, Goatley L, Pfeiffer DU, Dixon L. Dynamics of African swine fever virus shedding and excretion in domestic pigs infected by intramuscular inoculation and contact transmission. Vet Res (Faisalabad). 2014;45(1):93. https://doi.org/10.1186/PREACCEPT-1922992841132370
  18. Chenais E, Stahl K, Guberti V, Depner K. Identification of wild boar-habitat epidemiologic cycle in African swine fever epizootic. Emerg Infect Dis. 2018;24(4):810-812. https://doi.org/10.3201/eid2404.172127
  19. EFSA AHAW Panel. Scientific opinion on African swine fever. EFSA J. 2014;12:3628.
  20. OIE Technical Disease Card-African Swine Fever. Paris: OIE; 2013.
  21. Kolbasov D, Titov I, Tsybanov S, Gogin A, Malogolovkin A. African swine fever virus, Siberia, Russia, 2017. Emerg Infect Dis. 2018;24(4):796-798. https://doi.org/10.3201/eid2404.171238
  22. Costard S, Jones BA, Martinez-Lopez B, Mur L, de la Torre A, Martinez M, et al. Introduction of African swine fever into the European Union through illegal importation of pork and pork products. PLoS One. 2013;8(4):e61104. https://doi.org/10.1371/journal.pone.0061104
  23. Kim HJ, Lee MJ, Lee SK, Kim DY, Seo SJ, Kang HE, et al. African swine fever virus in pork brought into South Korea by travelers from China, August 2018. Emerg Infect Dis. 2019;25(6):1231-1233. https://doi.org/10.3201/eid2506.181684
  24. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. African Swine Fever [Internet]. Paris: OIE; http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/3.08.01_ASF/pdf. Updated 2019.
  25. Food and Agriculture Organization of the United Nations/World Organisation for Animal Health/World Bank. Good Practices for Biosecurity in the Pig Sector-Issues and Options in Developing and Transition Countries. FAO Animal Production and Health Paper No. 169. Rome: FAO; 2010.
  26. Podgorski T, Smietanka K. Do wild boar movements drive the spread of African swine fever? Transbound Emerg Dis. 2018;65(6):1588-1596. https://doi.org/10.1111/tbed.12910
  27. Sur JH. How far can African swine fever spread? J Vet Sci. 2019;20(4):e41. https://doi.org/10.4142/jvs.2019.20.e41
  28. Niederwerder MC, Stoian AM, Rowland RR, Dritz SS, Petrovan V, Constance LA, et al. Infectious dose of African swine fever virus when consumed naturally in liquid or feed. Emerg Infect Dis. 2019;25(5):891-897. https://doi.org/10.3201/eid2505.181495
  29. Blazquez E, Pujols J, Segales J, Rodriguez F, Crenshaw J, Rodriguez C, et al. Commercial feed containing porcine plasma spiked with African swine fever virus is not infective in pigs when administered for 14 consecutive days. PLoS One. 2020;15(7):e0235895. https://doi.org/10.1371/journal.pone.0235895
  30. Wang WH, Lin CY, Chang Ishcol MR, Urbina AN, Assavalapsakul W, Thitithanyanont A, et al. Detection of African swine fever virus in pork products brought to Taiwan by travellers. Emerg Microbes Infect. 2019;8(1):1000-1002. https://doi.org/10.1080/22221751.2019.1636615
  31. Ito S, Jurado C, Sanchez-Vizcaino JM, Isoda N. Quantitative risk assessment of African swine fever virus introduction to Japan via pork products brought in air passengers' luggage. Transbound Emerg Dis. 2020;67(2):894-905. https://doi.org/10.1111/tbed.13414
  32. Yoon H, Hong SK, Lee I, Yoo DS, Jung CS, Lee E, et al. Clinical symptoms of African swine fever in domestic pig farms in the Republic of Korea, 2019. Transbound Emerg Dis. Forthcoming 2020.
  33. Yu M, Morrissy CJ, Westbury HA. Strong sequence conservation of African swine fever virus p72 protein provides the molecular basis for its antigenic stability. Arch Virol. 1996;141(9):1795-1802. https://doi.org/10.1007/BF01718302
  34. Kim HJ, Cho KH, Ryu JH, Jang MK, Chae HG, Choi JD, et al. Isolation and genetic characterization of African swine fever virus from domestic pig farms in South Korea, 2019. Viruses. 2020;12(11):1237. https://doi.org/10.3390/v12111237
  35. Beltran-Alcrudo D, Arias M, Gallardo C, Kramer S, Penrith ML. African Swine Fever: Detection and Diagnosis - A Manual for Veterinarians. FAO Animal Production and Health Manual No. 19. Rome: FAO; 2017.
  36. Boklund A, Cay B, Depner K, Foldi Z, Guberti V, Masiulis M, et al. Epidemiological analyses of African swine fever in the European Union (November 2017 until November 2018). EFSA J. 2018;16(11):e05494.
  37. Pershin A, Shevchenko I, Igolkin A, Zhukov I, Mazloum A, Aronova E, et al. A long-term study of the biological properties of ASF virus isolates originating from various regions of the Russian Federation in 2013-2018. Vet Sci. 2019;6(4):99. https://doi.org/10.3390/vetsci6040099
  38. Danzetta ML, Marenzoni ML, Iannetti S, Tizzani P, Calistri P, Feliziani F. African swine fever: lessons to learn from past eradication experiences. A systematic review. Front Vet Sci. 2020;7:296. https://doi.org/10.3389/fvets.2020.00296
  39. Penrith ML, Guberti V, Depner K, Lubroth J. Preparation of African Swine Fever Contingency Plans. Rome: FAO; 2019.
  40. How Rapid Actions Can Curb the Spread of ASF: the Experience of Republic of Korea [Internet]. Paris: OIE; https://rr-asia.oie.int/en/projects/asf/asf-story-republic-of-korea/. Updated 2020.
  41. Tao D, Sun D, Liu Y, Wei S, Yang Z, An T, et al. One year of African swine fever outbreak in China. Acta Trop. 2020;211:105602. https://doi.org/10.1016/j.actatropica.2020.105602
  42. Nga BT, Tran Anh Dao B, Nguyen Thi L, Osaki M, Kawashima K, Song D, et al. Clinical and pathological study of the first outbreak cases of African swine fever in Vietnam, 2019. Front Vet Sci. 2020;7:392. https://doi.org/10.3389/fvets.2020.00392
  43. Xu Q. ASF Outbreak Management Approaches in China, Virtual Meeting of the Standing Group of Experts on African Swine Fever for Asia, April 2020 [Internet] https://rr-asia.oie.int/wp-content/uploads/2020/04/2-asf-outbreak-management-approaches-in-china.pdf. Updated 2020.
  44. Second Outbreak of ASF Found in China [Internet]. https://cahfs.umn.edu/news/second-outbreak-asffound-china. Updated 2020.
  45. Gao X, Liu T, Liu Y, Xiao J, Wang H. Transmission of African swine fever in China through legal trade of live pigs. Transbound Emerg Dis. Forthcoming 2020.
  46. Gong L, Xu R, Wang Z, Deng Q, Wang H, Zhang G. African swine fever recovery in China. Vet Med Sci. 2020;6(4):890-893. https://doi.org/10.1002/vms3.299
  47. Manso-Ribeiro J, Nunes-Petisca JL, Lopez-Frazao F, Sobral M. Vaccination against ASF. Bull Off Int Epizoot. 1963;60:921-937.
  48. Barasona JA, Gallardo C, Cadenas-Fernandez E, Jurado C, Rivera B, Rodriguez-Bertos A, et al. First oral vaccination of Eurasian wild boar against African swine fever virus genotype II. Front Vet Sci. 2019;6:137. https://doi.org/10.3389/fvets.2019.00137
  49. Borca MV, Ramirez-Medina E, Silva E, Vuono E, Rai A, Pruitt S, et al. Development of a highly effective african swine fever virus vaccine by deletion of the I177L gene results in sterile immunity against the current epidemic Eurasia strain. J Virol. 2020;94(7):e02017-e02019.
  50. Chen W, Zhao D, He X, Liu R, Wang Z, Zhang X, et al. A seven-gene-deleted African swine fever virus is safe and effective as a live attenuated vaccine in pigs. Sci China Life Sci. 2020;63(5):623-634. https://doi.org/10.1007/s11427-020-1657-9
  51. Kalpravidh W, Holley C. Strengthening the Cooperation on African Swine Fever Prevention and Control in the Asia-Pacific Region. OIE Regional Commission, 2019 [Internet]. https://doi.org/10.20506/TT.2989.
  52. Global Control of African Swine Fever, A GF-TADs Initiative (2020-2025). FAO & OIE [Internet]. https://www.oie.int/fileadmin/Home/eng/Animal_Health_in_the_World/docs/pdf/ASF/ASF_GlobalInitiative_web.pdf. Updated 2020.