Anti-inflammatory Effect of the Ostrich Extract Combined with Korean Herbal Medicine (II)

Kim, Ae-Jung;Yuh, Jung-Sook;Kim, Sun-Yeou;Park, Soo-Jin;Sung, Chung-Ja

  • Published : 20040800

Abstract

In this study, we investigated the anti-inflammatory effect of ostrich extract combined with Korean herbal medicine (OEKHM) in the carrageenan-induced rat footpad edema. Male Sprague-Dawley rats were used. There were two experimental groups: OEKHM and control. After treatment with oral doses of 3 mL/180g BW, the carrageenan-induced edema was slightly decreased in the OEKHM group. Moreover, OEKHM administration significantly suppressed both the inflammatory parameters, such as serum uric acid and the rheumatoid factor (RF), and the level of serum triglyceride (TG) and aspartic acid transaminase (AST) in carrageenan-induced paw edema in rats. On the contrary, OEKHM treatment increased the level of serum HDL-cholesterol. Based on the beneficial effect against either inflammation or serum cholesterol, we suggest OEKHM can be used as functional food for anti-inflammatory activity and hypolipidemic activity.

Keywords

References

  1. Korean Death Statistical Korean statistical association
  2. Symposium of Korean ostrich industry for intemational competitiveness Potentiation of ostrich for disease attracting the aged population Kim, A.J.
  3. Atherosclerosis v.16 no.1 Crude fiber, dietary fiber and atherosclerosis Trowell, H. https://doi.org/10.1016/0021-9150(72)90017-2
  4. Food Sci. Biotechnol. v.12 Mineral contents and anti-inflammatory effect of ostrich extract combined with Korean herb medicine Kim, A.J.;Yuh, C.S.;Lee, P.J.;Choi, M.K.;Kim, S.Y.
  5. J. Korean Soc. Food Sci. Nutr. v.27 Mineral contents and fatty acid composition of Jemsosojoo Kim, J.S.;Kim, K.P.;Lee, M.C.
  6. J. East Asian Soc. Diet. Life v.10 A study on the chemical composition. amino acid, and mineral contents of venison Park, C.I.;Kim, Y.J.;Kim, Y.K.;Kim, D.J.;Yuh, C.B.;Ahn, J.H.
  7. Proc. Soc. Exp. Biol. Med. v.111 Carrageenan-induced edema in hind paw of the rat as an assay for anti-inflammatory drugs Winter, C.A.;Risley, E.A.;Nuss, G.W. https://doi.org/10.3181/00379727-111-27849
  8. Indian J. Physiol. Pharmacol. v.36 Inhibition of lipid peroxidation and cholesterol levels in mice by curcumin Soudamini, K.K.;Unnikrishnan, M.C.;Soni, K.B.;Kuttan, R.
  9. Biochemical Pharmacology v.21 no.8 Lipid peroxide formation in experimental inflammation Sharma, S.C.;Mukhtar, H.;Sharma, S.K.;Krishna Murt, C.R. https://doi.org/10.1016/0006-2952(72)90118-9
  10. Clin. Sci. v.73 The gut in the acute phase response: changes in colonic and hepatic enzyme activity in response to dermal inflammation in the rat Hutton, C.W.;Corfield, A.P.;Clamp, J.R.;Oieppe, P.A.
  11. J. Korean Soc. Food Nutr. v.23 Anti-inflammatory and analgesic effects of the components from some edible plants Park, J.C.;Yu, Y.B.;Lee, J.H.;Kim, N.J.
  12. J. Korean Soc. Food Nutr. v.23 Studies on the chemical components and biological activities of edible plants in Korea (VI) Park, J.C.;Yu, Y.B.;Lee, J.H.;Kim, N.J.
  13. Circulation v.XLI no.SUP. Coronary heart disease in seven countries Keys, A.
  14. Clin. Chem. v.24 Simultaneous determination of serum cholesterol in high and low density lipoprotein with use of heparin, Ca and anion exchange resin Noma, A.;Nakayama, K.;Kita, M.;Okabe, H.
  15. Clin. Chem. v.25 Improved method for simultaneous determination of cholesterol in high and low density lipoprotein Noma, A.;Okabe, K.N.;Nakayya, Y.;Ueno, Y.;Shinlharam, H.
  16. Am. J. Clin. Pathol. v.28 Colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminase Reitman, S.;Frankel, S.A.
  17. SAS User's Guide SAS Institute, Inc.
  18. Biometrics v.11 no.1 Multiple range and multiple F test Duncan, Davide B. https://doi.org/10.2307/3001478