Archives of Pharmacal Research

  • 제28권10호
  • /
  • Pages.1127-1130
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  • 2005
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  • 0253-6269(pISSN)
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  • 1976-3786(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

A Phenolic Glucoside Isolated from Prunus serrulata var. spontanea and its Peroxynitrite Scavenging Activity

  • Jung Hyun Ah (Faculty of Food Science and Biotechnology, Pukyong National University) ;
  • Chung Hae Young (College of Pharmacy, Pusan National University) ;
  • Kang Sam Sik (Natural Product Research Institute and College of Pharmacy, Seoul National University) ;
  • Hyun Sook Kyung (Faculty of Food Science and Biotechnology, Pukyong National University) ;
  • Kang Hye Sook (Faculty of Food Science and Biotechnology, Pukyong National University) ;
  • Choi Jae Sue (Faculty of Food Science and Biotechnology, Pukyong National University)
  • 발행 : 2005.10.01
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초록

A new phenolic glucoside (1), pursargentoside, was isolated from the leaves of Prunus serrulata var. spontanea, along with three other known compounds, orobol 7-O-glucoside (2), $1{\beta}$, $2{\alpha}$, $3{\alpha}$, 24-tetrahydroxy-urs-12-en-28-oic acid (3), and chlorogenic acid (4). The structure of pursargentoside (1) was identified by spectroscopic data analysis including 1D and 2D NMR spectroscopy, as 2-O-${\beta}$-(6'-benzoyl)-glucopyranosyl o-(Z)-coumaric acid. Compounds 1, 2, and 4 exhibited ONOO- scavenging activity, whereas compound 3 was determined to be virtually inactive.

키워드

참고문헌

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