Korean Journal of Medicinal Crop Science (한국약용작물학회지)

The Korean Society of Medicinal Crop Science (한국약용작물학회)
권호 표지

Antioxidant Activities and Skin-Whitening Effects of Nano-encapsuled Water Extract from Rubus coreanus Miquel

복분자 추출물의 나노입자화를 통한 항산화 및 미백 효과 증진

  • Jeong, Hyang-Suk (College of Bioscience & Biotechnology, Kangwon National Univ.) ;
  • Han, Jae-Gun (College of Bioscience & Biotechnology, Kangwon National Univ.) ;
  • Han, Ji-Hye (College of Bioscience & Biotechnology, Kangwon National Univ.) ;
  • Kim, Young (College of Bioscience & Biotechnology, Kangwon National Univ.) ;
  • Oh, Sung-Ho (College of Bioscience & Biotechnology, Kangwon National Univ.) ;
  • Kim, Seoung-Seop (College of Bioscience & Biotechnology, Kangwon National Univ.) ;
  • Jeong, Myoung-Hoon (College of Bioscience & Biotechnology, Kangwon National Univ.) ;
  • Choi, Geun-Pyo (Department of Food Processing & Bakery, Gangwon Provincial Univ.) ;
  • Park, Uk-Yeon (Department of Food Processing & Bakery, Gangwon Provincial Univ.) ;
  • Lee, Hyeon-Yong (College of Bioscience & Biotechnology, Kangwon National Univ.)
  • 정향숙 (강원대학교 BT특성화학부대학) ;
  • 한재건 (강원대학교 BT특성화학부대학) ;
  • 하지혜 (강원대학교 BT특성화학부대학) ;
  • 김영 (강원대학교 BT특성화학부대학) ;
  • 오성호 (강원대학교 BT특성화학부대학) ;
  • 김승섭 (강원대학교 BT특성화학부대학) ;
  • 정명훈 (강원대학교 BT특성화학부대학) ;
  • 최근표 (강원도립대학 식품가공제과제빵과) ;
  • 박욱연 (강원도립대학 식품가공제과제빵과) ;
  • 이현용 (강원대학교 BT특성화학부대학)
  • Published : 2009.04.30
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Abstract

This study was performed to improve antioxidant activities and skin-whitening effects of Rubus coreanus Miquel extracts by nano-encapsulation. R. coreanus was extracted at $60^{\circ}C$ and encapsulated by lecithin and gelagine. Nano-encapsulated extracts showed highest free radical scavengering effect as 97.62% in adding sample ($500\;{\mu}g/m{\ell}$), compared to the extracts from conventional processes. It was showed strong inhibition effect on melanin production test by Clone M-3 cells as 55.23%. High inhibitory potency on tyrosinase was also measured as 155.8% by adding nano-sample of 1 $mg/m{\ell}$. The improvement of biological activity was demonstrated by real time confocal microscope. We could consider that the water soluble extracts of R. coreanus could be definitely enhanced by nano-encapsulated as a potent natural resources for antioxidant and skin-whitening agent.

Keywords

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