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Milk Containing BF-7 Enhances the Learning and Memory, Attention, and Mathematical Ability of Normal Persons

  • Kim, Do-Hee (Department of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Lee, Hyun-Jung (Department of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Choi, Gooi-Hun (Division of Animal Life Science, Konkuk University) ;
  • Kim, Ok-Hyeon (Department of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Lee, Kwang-Gill (Applied Entomology Division, Department of Sericulture and Entomology, National Academy of Agriculture Science) ;
  • Yeo, Joo-Hong (Applied Entomology Division, Department of Sericulture and Entomology, National Academy of Agriculture Science) ;
  • Lee, Jun-Young (Department of Psychiatry, College of Medicine, Seoul National University) ;
  • Lee, Sang-Hyung (Department of Neurosurgery, College of Medicine, Seoul National University, SMG-SNU Boramae Medical Center) ;
  • Youn, Young-Chul (Department of Neurology, College of Medicine, Chung-Ang University) ;
  • Lee, Jang-Han (Department of Psychology, College of Liberal Arts, Chung-Ang University) ;
  • Paik, Hyun-Dong (Division of Animal Life Science, Konkuk University) ;
  • Lee, Won-Bok (Department of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Kim, Sung-Su (Department of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Jung, Hee-Yeon (Department of Psychiatry, College of Medicine, Seoul National University)
  • Published : 2009.04.30

Abstract

Previous studies indicate that BF-7 enhances learning and memory in normal and elderly individuals. Here, we evaluated whether milk containing BF-7 (BF-7 milk) could improve the brain function, with thirty normal university students $(21{\pm}1.2 years)$. Two versions of the Paced Auditory Serial Addition Test were used under double-blinded conditions to measure the efficacy of BF-7 milk on learning and memory, especially working memory and attention, and on mathematical ability. As a result, BF-7 milk improved the accuracy of the task more than 3-fold. Furthermore, BF-7 milk protected cultured neuronal cells from 3-hydroxykynurenine, a normal endogenous brain stress agent. These results indicate that BF-7 milk enhances memory, attention and mathematical ability in normal persons.

Keywords

References

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