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A Study on Oriental Medicine Diagnostic Application through Analysis of Heart Rate Variability in Polycystic Ovary Syndrome Females

PCOS 여성의 HRV 특성 분석을 통한 한의학적 진단 활용성에 관한 연구

  • Lee, Mi-Joo (KangNam Kyung-Hee Oriental Hospital) ;
  • Hwang, Deok-Sang (KangNam Kyung-Hee Oriental Hospital) ;
  • Lee, Jin-Moo (Dept. of Oriental Gynecology, College of Oriental Medicine, Kyung-Hee University) ;
  • Lee, Chang-Hoon (KangNam Kyung-Hee Oriental Hospital) ;
  • Cho, Jung-Hoon (Dept. of Oriental Gynecology, College of Oriental Medicine, Kyung-Hee University) ;
  • Jang, Jun-Bock (Dept. of Oriental Gynecology, College of Oriental Medicine, Kyung-Hee University) ;
  • Lee, Khung-Sub (KangNam Kyung-Hee Oriental Hospital)
  • 이미주 (강남 경희 한방병원) ;
  • 황덕상 (강남 경희 한방병원) ;
  • 이진무 (경희대학교 한의과대학 한방부인과교실) ;
  • 이창훈 (강남 경희 한방병원) ;
  • 조정훈 (경희대학교 한의과대학 한방부인과교실) ;
  • 장준복 (경희대학교 한의과대학 한방부인과교실) ;
  • 이경섭 (강남 경희 한방병원)
  • Received : 2010.10.25
  • Accepted : 2010.11.09
  • Published : 2010.11.30

Abstract

Purpose: The aim of the study was to compare the characteristics of the autonomic innervation of the heart in polycystic ovary syndrome(PCOS) patients with regulary cycling controls. Methods: We studied 21 patients visiting $\bigcirc\bigcirc$hospital from 25th June 2009 to 25th June 2010. The subjects were categorized in two groups, 11 PCOS patients and 10 healthy regularly cycling controls. We studied the difference of Heart rate variability (HRV) between two groups by Independent samples T-test using SPSS for windows(version 17.0). Results: The Standard deviation of all normal R-R intervals (SDNN), The spuare root of the sum of the spuare of difference between adjacent normal R-R intervals (RMS-SD) of PCOS group was non-significantly lower than non-PCOS group. High frequency power (HF) and Normalized high frequency power (HF norm) of PCOS group was significantly higher than non-PCOS group. Normalized low frequency power (LF norm) of PCOS was signficantly lower than non-PCOS group. The results means increased sympathetic and decreased vagal modulation. Total power (TP), Very low frequency power (VLF) of PCOS group was non-significantly lower than non-PCOS group. Low frequency power (LF), LF/HF ratio of PCOS group was non-significantly higher than non-PCOS group. Conclusion: The results suggest that PCOS can be related to decreased activity of parasympathetic nervous system.

Keywords

References

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