Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
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Blood Heavy Metal Concentrations of Korean Adults by Seafood Consumption Frequency: Using the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV), 2008

국민건강영양조사 제4기 2차년도 (2008)를 이용한 어패류 섭취빈도에 따른 한국 성인의 혈중 중금속 농도 조사

  • 김영아 (중앙대학교 자연과학대학 식품영양학과) ;
  • 김영남 (덕성여자대학교 자연과학대학 식품영양학과) ;
  • 조경동 (푸드원텍(주)) ;
  • 김미영 (중앙대학교 자연과학대학 식품영양학과) ;
  • 김은진 (중앙대학교 자연과학대학 식품영양학과) ;
  • 백옥희 (디미(주)) ;
  • 이복희 (중앙대학교 자연과학대학 식품영양학과)
  • Received : 2011.09.21
  • Accepted : 2011.12.05
  • Published : 2011.12.31
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Abstract

To determine blood heavy metal concentrations by seafood consumption in Korean adults, blood cadmium, mercury, and lead concentrations in a representative sample of 1,709 Koreans participated in the Fourth Korea National Health and Nutrition Examination Survey (KHANES IV-2) in 2008 were analyzed by age and seafood consumption frequency. The mean blood cadmium, mercury, and lead concentrations were $1.14{\pm}0.73{\mu}g/L$, $5.50{\pm}3.83{\mu}g/L$, and $2.56{\pm}1.22{\mu}g/dL$, respectively. The subjects aged ${\geq}$ 50 years had significantly higher blood cadmium concentrations than the subjects aged 20~39 years. Blood mercury concentrations of the 50's were significantly higher than those of the 20's and 30's (p < 0.05). Approximately, 43% of males and 22% of females had blood mercury concentrations > $5.8{\mu}g/L$ which is a blood mercury level equivalent to the current Reference Dose. Only 2 subjects had lead concentrations > $10{\mu}g/dL$, the standard lead level by the Centers for Disease Control and Prevention, USA. The subjects consuming pollack, mackerel, anchovy, corvina, shellfish, and salted seafood at least once a week had significantly higher mercury concentrations than the subjects consuming those seafoods less than once a month. However, there were no clear relationships between blood cadmium and lead concentrations and seafood consumption frequencies.

Keywords

References

  1. Jun JY, Xu XM, Jeong IH. Heavy metal contents of fish collected from the Korean coast of the East Sea (Donghae). J Korean Fish Soc 2007; 40(6): 362-366
  2. Lee SR, Lee MG. Contamination and risk analysis of heavy metals in Korean foods. J Food Hyg Saf 2001; 16(4): 324-332
  3. Kris-Etherton PM, Harris WS, Appel LJ. American Heart Association. Nutrition Committee. Fish consumption, fish oil, omega- 3 fatty acids, and cardiovascular disease. Circulation 2002; 106(21): 2747-2757 https://doi.org/10.1161/01.CIR.0000038493.65177.94
  4. Smith KM, Barraj LM, Kantor M, Sahyoun NR. Relationship between fish intake, n-3 fatty acids, mercury and risk markers of CHD (National Health and Nutrition Examination Survey 1999- 2002). Public Health Nutr 2009; 12(8): 1261-1269 https://doi.org/10.1017/S1368980008003844
  5. Kim EH, Kim IK, Kwon JY, Koo JS, Hwang HS, Kim SK, Park YW, Noh JH, Lee DH. The effect of fish consumption on blood mercury level in pregnant women. Korean J Obstet Gynecol 2005; 48(11): 2527-2534
  6. United States Environmental Protection Agency. Human exposure. [accessed 2011 Oct 19]. Available from: http://www.epa. gov/mercury/ exposure.htm
  7. Korea Food & Drug Administration. Cadmium. [accessed 2011 Mar 15]. Available from: http://www.foodnara.go.kr/portal/site/ kfdaportal/infodanger series/
  8. Korea Food & Drug Administration. Mercury. [accessed 2011 Mar 15]. Available from: http://www.foodnara.go.kr/portal/site/ kfdaportal/infodanger series/
  9. Korea Food & Drug Administration. Lead. [accessed 2011 Mar 15]. Available from: http://www.foodnara.go.kr/portal/site/kfdaportal/ infodanger series/
  10. National Institute of Food and Drug Safety Evaluation. [accessed 2011 Apr 21]. Available from: http://www.nifds.go.kr/nifds/03_ info/info01.jsp?m ode=view&article_ no=2645&pager.offset= 140&board_no=76
  11. Korea Centers for Disease Control and Prevention. The Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV-2). Cheongwon; 2008
  12. Kim CW, Kim YW, Chae CH, Son JS, Park SH, Koh JC, Kim DS. The effects of the frequency of fish consumption on the blood mercury levels in Koreans. Korean J Occup Environ Med 2010; 22(2): 114-121
  13. Agency for Toxic Substances & Disease Registry. Lead toxicity. What are the U.S. standards for lead levels? [accessed 2011 Mar 8]. Available from: http://www.atsdr.cdc.gov/csem/csem.asp?csem= 7&po=8
  14. Kim NS, Lee BK. Blood total mercury and fish consumption in the Korean general population in KNHANES ΙΙΙ, 2005. Sci Total Environ 2010; 408(20): 4841-4847 https://doi.org/10.1016/j.scitotenv.2010.06.026
  15. Lee MS, Park SK, Hu H, Lee S. Cadmium exposure and cardiovascular disease in the 2005 Korea National Health and Nutrition Examination Survey. Environ Res 2011; 111(1): 171-176 https://doi.org/10.1016/j.envres.2010.10.006
  16. Jo EM, Kim BG, Kim YM, Yu SD, You CH, Kim JY, Hong YS. Blood mercury concentration and related factors in an urban coastal area in Korea. J Prev Med Public Health 2010; 43(5): 377- 386 https://doi.org/10.3961/jpmph.2010.43.5.377
  17. Myers GJ, Davidson PW, Strain JJ. Nutrient and methyl mercury exposure from consuming fish. J Nutr 2007; 137(12): 2805-2808
  18. Cha YS, Ham HJ, Lee JI, Lee JJ. Heavy metals in fishery products, sold at fish markets in Seoul. J Food Hyg Safe 2001; 16(4): 315- 323
  19. Fang F, Kwee LC, Allen KD, Umbach DM, Ye W, Watson M, Keller J, Oddone EZ, Sandler DP, Schmidt S, Kamel F. Association between blood lead and the risk of amyotrophic lateral sclerosis. Am J Epidemiol 2010; 171(10): 1126-1133 https://doi.org/10.1093/aje/kwq063
  20. Son JY, Lee J, Paek D, Lee JT. Blood levels of lead, cadmium, and mercury in the Korean population: results from the second Korean national human exposure and bio-monitoring examination. Environ Res 2009; 109(6): 738-744 https://doi.org/10.1016/j.envres.2009.03.012
  21. Mahaffey KR, Clickner RP, Bodurow CC. Blood organic mercury and dietary mercury intake: National health and nutrition examination survey, 1999 and 2000. Environ Health Perspect 2004; 112(5): 562-570
  22. Schober SE, Sinks TH, Jones RL, Bolger PM, Mcdowell M, Osterloh J, Garrett ES, Canady RA, Dillon CF, Sun Y, Joseph CB, Mahaffey KR. Blood mercury levels in US children and women of childbearing age, 1999-2000. JAMA 2003; 289(13): 1667-1674 https://doi.org/10.1001/jama.289.13.1667
  23. Hightower JM, O'Hare A, Hernandez GT. Blood mercury reporting in NHANES: identifying Asian, Pacific Islander, Native American, and multiracial groups. Environ Health Perspect 2006; 114(2): 173-175 https://doi.org/10.1289/ehp.8464
  24. Lincoln RA, Shine JP, Chesney EJ, Vorhees DJ, Grandjean P, Senn DB. Fish consumption and mercury exposure among Louisiana recreational anglers. Environ Health Perspect 2011; 119(2): 245-251
  25. Kim NS, Lee BK. National estimates of blood lead, cadmium, and mercury levels in the Korean general adult population. Int Arch Occup Environ Health 2011; 84(1): 53-63 https://doi.org/10.1007/s00420-010-0522-6
  26. Moon CS. Evaluation of Cd and Pb intake and exposure routes in some Korean women. J Environ Health Sci 2007; 33(5): 353-358
  27. Kim JY, Kim JH, Kim HW, Roh JH, Lee KH, Cheon BC, Nam SM. A review of lead poisoning cases reported for recent 30 years in korea. Korean J Med 2004; 66(6): 617-624
  28. The Korean Nutrition Society. Dietary reference intakes for Koreans, 1st revision. Seoul; 2010. p.529
  29. Sho YS, Kim J, Chung SY, Kim M, Hong MK. Trace metal contents in fishes and shellfishes and their safety evaluations. J Korean Soc Food Sci Nutr 2000; 29(4): 549-554

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