Pediatric Gastroenterology, Hepatology & Nutrition

The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition (대한소아소화기영양학회)
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Changing Prevalence of Helicobacter pylori Infections in Korean Children with Recurrent Abdominal Pain

  • Jang, Kyung Mi (Department of Pediatrics, Kyungpook National University School of Medicine) ;
  • Choe, Byung-Ho (Department of Pediatrics, Kyungpook National University School of Medicine) ;
  • Choe, Jae Young (Department of Pediatrics, Kyungpook National University School of Medicine) ;
  • Hong, Suk Jin (Department of Pediatrics, Kyungpook National University School of Medicine) ;
  • Park, Hyo Jung (Department of Pediatrics, Kyungpook National University School of Medicine) ;
  • Chu, Mi Ae (Department of Pediatrics, Kyungpook National University School of Medicine) ;
  • Cho, Seung Man (Department of Pediatrics, Kyungpook National University School of Medicine) ;
  • Kim, Jung Mi (Department of Pediatrics, Kyungpook National University School of Medicine)
  • Received : 2014.09.22
  • Accepted : 2014.10.21
  • Published : 2015.03.30
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Abstract

Purpose: The aim of this study is to investigate the changing prevalence rate of Helicobacter pylori infection in children, of different age groups, with recurrent abdominal pain over a 10-year period. Methods: Children with recurrent abdominal pain who visited the pediatric outpatient clinic at university hospital were screened for H. pylori. Children were divided into 3 age categories of 4-5, 6-11, and 12-16 years. To study the changes in the annual prevalence rates of H. pylori infection, the study period was divided into 3 time periods: 2004-2007, 2008-2010, and 2011-2014. Urea breath test was performed for all children aged 4-16 years, with a cut-off value of 4.0‰ for children aged ${\geq}6$ years and 7‰ for children aged <6 years. Results: A total of 2,530 children (1,191 boys) with a mean age of $10.0{\pm}3.0years$ (range, 4.0-16.9 years) were included in the study. The total prevalence of H. pylori infection was 7.4% (187/2,530). The prevalence rate of H. pylori infection in children with recurrent abdominal pain was 8.0% (70/873) in 2004-2007, 7.7% (51/666) in 2008-2010, and 6.7% (66/991) in the 2011-2014. Nevertheless, a significant difference was observed in the prevalence rate between children <12 years old and ${\geq}12$ years of age (p=0.018). Conclusion: The prevalence of H. pylori infection in Korean children with recurrent abdominal pain was 7.4%, showing no significant decrease in the last 11 years; however, the prevalence rate in children <12 years old was significantly lower than that in those ${\geq}12$ years old.

Keywords

References

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