Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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A Review on Experimental Studies of Parkinson's Disease in Korean Medical Journals

파킨슨병에 대한 국내 한의학 관련 실험 연구 동향

  • Joo, Hwan Soo (Department of Oriental Neuropsychiatry, Jaseng Hospital of Korean Medicine) ;
  • Yu, Ok Cheol (Department of Oriental Neuropsychiatry, Jaseng Hospital of Korean Medicine) ;
  • Han, Chang (Department of Oriental Neuropsychiatry, Jaseng Hospital of Korean Medicine) ;
  • Yang, Kyu Jin (Department of Acupuncture and Moxibustion, Jaseng Hospital of Korean Medicine) ;
  • Lee, Sung Yub (Department of Oriental Obsterics and Gynecology, Jaseng Hospital of Korean Medicine) ;
  • Moon, Hye Yeon (Department of Oriental Obsterics and Gynecology, Jaseng Hospital of Korean Medicine)
  • 주환수 (자생한방병원 한방신경정신과) ;
  • 유옥철 (자생한방병원 한방신경정신과) ;
  • 한창 (자생한방병원 한방신경정신과) ;
  • 양규진 (자생한방병원 침구과) ;
  • 이성엽 (자생한방병원 한방부인과) ;
  • 문혜연 (자생한방병원 한방부인과)
  • Received : 2017.07.10
  • Accepted : 2017.08.29
  • Published : 2017.09.30
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Abstract

Objectives: The purpose of this study is to review experimental studies of Parkinson's Disease in Korean medical journals, which have been published since 1990. Methods: Experimental studies related to Parkinson's disease published in Korean medical journals, registered with Korea research foundation, were searched. Articles were grouped into journal of publication, subject, and publication year. Experimental study subjects and models were analysed. Results and Conclusions: Twenty-two articles about experimental studies of Parkinson's Disease in Korean medical journals were included in our review. There were 13 articles in which herbs were used for treatment, 4 articles in which bee venom was used for treatment, 4 articles in which acupuncture was used for treatment, and 1 article in which pharmacopuncture was used for treatment. Most of the studies used experimental models of MPTP-induced Parkinson's disease and MTT assay was used to analyse cell toxicity and cell viability. Pole test, rotarod test, Morris water maze test, and forced swimming test were commonly used to analyse MPTP-induced behavioral deficits in animals. Analysis on experimental studies of Parkinson's disease was categorized into the subjects of dopaminergic cell protective effect, cell-apoptosis protectiveness, anti-inflammatory effect, and anti-oxidative effect.

Keywords

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