Journal of Ginseng Research

The Korean Society of Ginseng (고려인삼학회)
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Pharmacological potential of ginseng and its major component ginsenosides

  • Ratan, Zubair Ahmed (Department of Biomedical Engineering, Khulna University of Engineering and Technology) ;
  • Haidere, Mohammad Faisal (Department of Public Health and Informatics, Bangabandhu Sheikh Mujib Medical University) ;
  • Hong, Yo Han (Department of Integrative Biotechnology, Sungkyunkwan University) ;
  • Park, Sang Hee (Department of Biocosmetics, Sungkyunkwan University) ;
  • Lee, Jeong-Oog (Department of Aerospace Information Engineering, Bio-Inspired Aerospace Information Laboratory, Konkuk University) ;
  • Lee, Jongsung (Department of Integrative Biotechnology, Sungkyunkwan University) ;
  • Cho, Jae Youl (Department of Integrative Biotechnology, Sungkyunkwan University)
  • Received : 2019.12.31
  • Accepted : 2020.02.25
  • Published : 2021.03.01
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Abstract

Ginseng has been used as a traditional herb in Asian countries for thousands of years. It contains a large number of active ingredients including steroidal saponins, protopanaxadiols, and protopanaxatriols, collectively known as ginsenosides. In the last few decades, the antioxidative and anticancer effects of ginseng, in addition to its effects on improving immunity, energy and sexuality, and combating cardiovascular diseases, diabetes mellitus, and neurological diseases, have been studied in both basic and clinical research. Ginseng could be a valuable resource for future drug development; however, further higher quality evidence is required. Moreover, ginseng may have drug interactions although the available evidence suggests it is a relatively safe product. This article reviews the bioactive compounds, global distribution, and therapeutic potential of plants in the genus Panax.

Keywords

Acknowledgement

This work was supported by the BK21 plus program and the Basic Science Research Program (2017R1A6A1A03015642) of the National Research Foundation of Korea (NRF), funded by the Ministry of Education, and by a grant in 2018 to J.Y.C. from the Korean Society of Ginseng, Republic of Korea.

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