Korean Journal of Medicinal Crop Science (한국약용작물학회지)

The Korean Society of Medicinal Crop Science (한국약용작물학회)
권호 표지
DOI QR코드

DOI QR Code

Enhancement of Antioxidant Activities and Whitening Effect of Acer mono Sap Through Nano Encapsulation Processes

고로쇠 수액 나노입자의 항산화 활성 및 미백 효과의 증진

  • Kim, Ji-Seon (Medical & Bio-Material Research Center and College of Bioscience and Biotechnology, Kangwon National University) ;
  • Seo, Yong-Chang (Medical & Bio-Material Research Center and College of Bioscience and Biotechnology, Kangwon National University) ;
  • Choi, Woon-Yong (College of Bioscience and Biotechnology, Kangwon National University) ;
  • Kim, Hack-Soo (SOMANG Cosmetics) ;
  • Kim, Bo-Hyeon (SOMANG Cosmetics) ;
  • Shin, Dae-Hyeon (SOMANG Cosmetics) ;
  • Yoon, Chang-Soon (Shebah Biotech Co., Hallym Business Incubator/Industry-University) ;
  • Lim, Hye-Won (Shebah Biotech Co., Hallym Business Incubator/Industry-University) ;
  • Ahn, Ju-Hee (College of Bioscience and Biotechnology, Kangwon National University) ;
  • Lee, Hyeon-Yong (Medical & Bio-Material Research Center and College of Bioscience and Biotechnology, Kangwon National University)
  • 김지선 (의료바이오신소재융복합연구사업단 강원대학교 바이오산업공학부) ;
  • 서용창 (의료바이오신소재융복합연구사업단 강원대학교 바이오산업공학부) ;
  • 최운용 (강원대학교 바이오산업공학부) ;
  • 김학수 (소망화장품) ;
  • 김보현 (소망화장품) ;
  • 신대현 (소망화장품) ;
  • 윤창순 (세바바이오텍) ;
  • 임혜원 (세바바이오텍) ;
  • 안주희 (강원대학교 바이오산업공학부) ;
  • 이현용 (의료바이오신소재융복합연구사업단 강원대학교 바이오산업공학부)
  • Received : 2011.05.12
  • Accepted : 2011.06.22
  • Published : 2011.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

In this study, we investigated antioxidant activities and whitening effects of Acer mono sap by encapsulation of nanoparticles. Acer mono sap was through ultra high pressure process and then encapsulated by lecithin. Nano-encapsulated The nanoparticles of Acer mono sap showed highest free radical scavengering effect as 89.7% in adding sample (1.0 mg/ml), compared to sap of non-encapsulation. It was showed strong inhibition effect on melanin production test by Clone M-3 cells as 47.8%. High inhibitory of tyrosinase was also measured as 85.8% by adding lecithin nano-particle of 1.0 mg/ml. The nano-particles also showed 14.8% of low cytotoxicity against human normal fibroblast cells in adding 1.0 mg/ml of the highest concentration. These results indicate that Acer mono sap may be a source of cosmetic agents capable of improving whitening effect and antioxidant activites.

Keywords

References

  1. Ahn WH. (1975). Color index and coloring substances in Korean sugar maple, Acer mono Max. syrup. Journal of Korea Forest Research. 26:7-12
  2. Aroca P, Urabe K, Kobayashi T, Tsukamoto K and Hearing VJ. (1993). Melanin biosynthesis patterns following hormonal stimulation. Journal of Biological Chemistry. 268:25650-25655.
  3. Bernadette EK, Marianne D and Bernhard P. (1998). Protective effect against sunburn of conbined systemic ascorbic acid and α-tocopherol. Experimental Dermatology. 38:45-48.
  4. Cabane J, Chazara S and Garcia CF. (1994). Kojic acid, a cosmetic skin whitening agent, is a slow-binding inhibitor of catecholase activity of tyrosinase. Journal of Pharmacy and Pharmacology. 46:982-985. https://doi.org/10.1111/j.2042-7158.1994.tb03253.x
  5. Halliwell B. (1991). Drug antioxidant effect. A basis for drug selection? Drugs. 42:569-605. https://doi.org/10.2165/00003495-199142040-00003
  6. Hwang JS, Shin HJ, Noh HS, Choi HJ, Ahn SM, Park DS, Kim DH, Lee BG, Chang IS and Kang HH. (2002). The inhibitory effects of 3,4,5-Trimethoxy cinamate thymol ester(TCTE, $Melsolv{\circledR}$) on Melanogenesis. Journal of the Society of Cosmetic Scientist of Korea. 28:135-149.
  7. Jeong SW, Lee NK, Kim SJ and Han DS. (1995). Screening of tyrosinase inhibitor from plants. Journal of Food Science and Nutrition. 27:891-896.
  8. Kang HI, Kim JY, Kwon SJ, Park KW, Kang JS and Seo KI. (2010). Antioxidative effects of peanut sprout extracts. Journal of the Korean Society of Food Science and Nutrition. 39:941-946. https://doi.org/10.3746/jkfn.2010.39.7.941
  9. Kang KC, Lee CI, Pyo HB and Jeong NH. (2005). Preparation and characterization of nano-liposomes using phosphatidylcholine. Journal of Industrial and Engineering Chemistry. 11:847-851.
  10. Kim CM, Jung DL and Sheo HJ. (1991). A study on the ingredients in the sap of Acer mono Max. and Betula costata T. in Mt. Jiri area. Journal of the Korean Society of Food Science and Nutrition. 20:479-482.
  11. Kim DM and Kwak HS. (2004). Nano food materials and approchable development of nanofunctional dairy products Korean Journal of Dairy Technology Science. 22:1-12.
  12. Kim JH, Jeong CH and Shim KW. (2003). Biological activities of solvent fractions of capsicum annuum leaves. Korean Journal of Food Preservation. 10:540-546.
  13. Kim NI. (2005). Role of vitamines and minerals on skin care and beauty. Food Science and Industry. 38:16-25.
  14. Kim YR. (2006). Nanotechnology in food safety. Food Science and Industry. 41:10-16.
  15. Korea Forest Service. (2002). Statistical Yearbook of forestry. Korea Forest Service. 32:407.
  16. Lee CH, Nho JW, Hwang IG, Shin CS, Lee JS and Jeong HS. (2010). Shelf-life extension of Acer mono sap using ultra filtration. Journal of Korean Society Food Science Nurition. 39:455-460. https://doi.org/10.3746/jkfn.2010.39.3.455
  17. Lee GW, Lee JY and Cho YH. (2010). Whitening effect of the extracts from juglans mandshurica. Korean Journal of Biotechnology and Bioengineering. 25:18-24.
  18. Lee TB. (1982). Illustrated flora of Korea. Hyangmunsa. 522-524.
  19. Lim E, Browing J, MacGregor D, Davis ID and Cebon JS. (2006). Desmoplastic melanoma: comparison of expression of differentiation antigens and cancer testis antigens. Melanoma Research. 16:347-355. https://doi.org/10.1097/01.cmr.0000222588.22493.3f
  20. Maeda K and Fukuda M. (1991). In vitro effectiveness of several whitening cosmeticcomponents in human melanocytes. Journal of Society Cosmetic Chemistry. 42:361-368.
  21. Moon HS and Kwon SD. (2004). Sap collection and major compounds of Acer okamotoanum Nakai native in Ullungdo. Korean Journal of Medicinal Crop Science. 12:249-254.
  22. Mosmann T. (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods. 65:55-63. https://doi.org/10.1016/0022-1759(83)90303-4
  23. Oyaizu M. (1986). Studies on products of browning reaction: antioxidative activities of products of browning reaction prepared from glucosamine. Japanese Journal of Nutrition. 44:307-315. https://doi.org/10.5264/eiyogakuzashi.44.307
  24. Park SN. (1997). Skin aging and antioxidants. Journal of the Society of Cosmetic Scientists of Korea. 23:75-132.
  25. Park YJ, Kim HJ and Heo BG. (2007). Anti-microbial. antioxidant and anti-inflammation effect with of the flower and the young seaf extracts in oriental cherry plant. Korea Society for People, Plants and Environment. 10:43-49.
  26. Saxena A, Sachin K, Bohidar HB and Verma AK. (2005). Effect of molecular weight heterogeneity on drug encapsulation efficiency of gelatin nano-particles. Colloids and Surfaces B: Biointerfaces. 45:42-48. https://doi.org/10.1016/j.colsurfb.2005.07.005
  27. Seo HS, Chung BH and Cho YG. (2008). Antioxidant and anticancer effects of agrimony (Agrimonia pilosa L.) and chinese lizardtail (Saururus chinensis Baill). Korean Journal of Medicinal Crop Science. 16:139-143.
  28. Tobin D and Thody AJ. (1994). The superoxide anion may mediate short but not long term effects of ultraviolet radiation on melanogenesis. Journal of the American Academy of Dermatology. 3:99-105.
  29. Tomita K, Oda N, Kamel M, Miyaki T and Oki T. (1990). A new screening method for melanin biosynthesis inhibitor using Streptomyces bikiniensis. Journal of Antibiotics. 12: 1601-1605.
  30. Yoon SL, Jo JS and Kim TO. (1992). Utilization and tapping of the sap from birches and maples. Mokchae Konghak. 20:15-20.

Cited by

  1. Effect of Various Pear Cultivars at Different Fruit Development Stages on Antioxidant and Whitening Activities vol.48, pp.1, 2016, https://doi.org/10.9721/KJFST.2016.48.1.59
  2. Germination Characteristics and Early Growth of Acer pictum subsp. mono (Maxim.) H. Ohashi by Harvesting Dates vol.24, pp.1, 2016, https://doi.org/10.7783/KJMCS.2016.24.1.21
  3. Screening of Skin Whitening Activity of Codonopsis lanceolata Extract by Complex Steaming Process vol.21, pp.1, 2013, https://doi.org/10.7783/KJMCS.2013.21.1.54
  4. Physicochemical Characteristics and Nutritional Components of Goroshoe (Acer mono Max.) Sap with Collection Periods vol.40, pp.10, 2011, https://doi.org/10.3746/jkfn.2011.40.10.1482
  5. The Effect of Cosmetic on Anti-Wrinkle of Acer mono Sap vol.21, pp.4, 2013, https://doi.org/10.7783/KJMCS.2013.21.4.262
  6. Suppressive Effect of Acanthopanax sessiliflorus Extract on the DNA and Cell Damage by Dieldrin vol.20, pp.4, 2012, https://doi.org/10.7783/KJMCS.2012.20.4.245