Journal of Society of Preventive Korean Medicine (대한예방한의학회지)

Society of Preventive Korean Medicine (대한예방한의학회)
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Anti-Obesity Effect of Herbal Mixture Powder and Water Extracts in Mice Fed a High Fat Diet

나복자, 의이인, 백복령, 다엽, 차전자피로 구성된 혼합분말제(HP)와 진피, 산사, 옥미수, 양총피로 구성된 혼합열수추출물(HE)이 고지방식이로 유도된 비만마우스에 미치는 항비만 효과

  • Youn, Jedong (Department of Venture Management, Graduate School of Venture, Hoswo University) ;
  • Choi, Yunhee (Department of Oriental Medicine & Healthcare, Wonkwang Digital University)
  • 연제동 (호서대학교 벤처전문대학원) ;
  • 최윤희 (원광디지털대학교 한방건강학과)
  • Received : 2015.03.16
  • Accepted : 2015.04.12
  • Published : 2015.04.30
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Abstract

Objective : This study was conducted to investigate anti-obesity effects of mixed-Powder(Raphani Semen, Coicis Semen, Poria, Plantaginis Testa & Theae folium)(HP) & mixed water extract(Citri Pericarpium, Crataegi Fructus, Maydis Stigma, Allium Skin) (HE) in mice fed a high-fat diet. Method : 50 Female ICR mice were divided into six groups; Normal group (Ve), high-fat diet group (Po), Po+HP(0.6g/kg) group(HP), Po+HE(1g/kg) group(HE), Po+(HP+HE) group(HPE), Po+(HP+HE)*2 group(DHPE). For 8 weeks, these groups were fed their respective diets. Body weight, liver weight and weights of adipose tissues, GOT/GPT index changes & Blood Glucose index changes were measured respectively. Lipid profiles in serum were analyzed by kit of blood. Results : Groups HP, HE, HPE, DHPE had significantly reduced body weight, liver weight, adipose tissue weights and GOT/GPT index, blood glucose index compared to the Po group. Also, serum triglyceride and total cholesterol, low density lipoprotein, were significantly reduced when compared to the Po group. Group G1 had significantly increased high density lipoprotein levels. Conclusion : Mixed powder (HP) & mixed water extract (HE) show anti-obesity effects in mice fed a high-fat diet.

Keywords

Acknowledgement

Supported by : 원광디지털대학교

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