Journal of Pharmacopuncture (대한약침학회지)

KOREAN PHARMACOPUNCTURE INSTITUTE (대한약침학회)
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Biological Activities of Scolopendrid Pharmacopuncture

수순(水醇)추출법으로 조제된 오공 약침액의 생리활성 효과

  • Kim, Sung-Chul (Dept. of Acupuncture & Moxibustion, Gwang-Ju Oriental Medical Hospital, Wonkwang University) ;
  • Seo, Geun-Young (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University) ;
  • Lee, Sung-Won (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University) ;
  • Park, Sung-Joo (Dept. of herbology, school of Oriental Medicine, Wonkwang University) ;
  • Kim, Jae-Hyo (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University) ;
  • Ahn, Seong-Hun (Dept. of Meridian & Acupoint, college of Oriental Medicine, Wonkwang University) ;
  • Hwang, Sung-Yeoun (Korea Bio Medical Science institute)
  • 김성철 (원광대학교 광주한방병원 침구과) ;
  • 서근영 (원광대학교 한의과대학 경혈학교실) ;
  • 이성원 (원광대학교 한의과대학 경혈학교실) ;
  • 박성주 (원광대학교 한의과대학 본초학교실) ;
  • 김재효 (원광대학교 한의과대학 경혈학교실) ;
  • 안성훈 (원광대학교 한의과대학 경혈학교실) ;
  • 황성연 (한국전통의학연구소)
  • Received : 2010.05.19
  • Accepted : 2010.09.07
  • Published : 2010.09.30
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Abstract

Reactive Oxygen Species(ROS) are continuously produced at a high rate as a by-product of aerobic metabolism. Since tissue damage by free radical increases with age, the reactive oxygen species(ROS) such as hydrogen peroxide($H_2O_2$), nitric oxide(NO). Several lines of evidence provided that ROS appears to cause to develop aging-related various diseases such as cancer, arthritis, cardiovascular disease. Our reserch objective was to examine the in vitro biological activity of Scolopendrid Pharmacopuncture, including the total poly-phenol content, DPPH radical scavenging, ABTS radical scavenging, Superoxide dismutase(SOD)-like activity, Nitrite scavenging ability. The total poly-phenol contents of Scolopendrid Pharmacopuncture was 35.859mg/L. Elctron donation ability on DPPH was 36.82%. The 2,2'-azinobis-3-ehtlbezothiazoline-6-sulfonic acid radical decolorization (ABTS) was 84.7%. The superoxide dismutase (SOD)-like activities of Scolopendrid Pharmacopuncture was 44.33%. The nitrite scavenging effects were pH dependent, and were highest at pH 1.5(45.2%) and lowest at pH 6.0(11.3%). We conclude that Scolopendrid Pharmacopuncture may be useful as potential sources of antioxidant.

Keywords

References

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